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Entry Nos. 900–999

99 Garrison-Morton entries in this range.

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1661

#760

De pulmonibus observations anatomicae.

Discovery of the capillary circulation. Malpighi demonstrated that the pulmonary tissues are vesicular in nature and showed that the trachea ends in bronchial filaments. His De pulmonibus includes his demonstration of…

1910

#900

Studies on isoagglutinins and isohemolysins.

Moss showed that the blood of all individuals could be placed into one of four groups. His classification has been the one most commonly used until recently. The work was similar to that of Janský and completed before…

1910

#901

The variation in the sizes of red blood cells.

Price-Jones described a method for the direct measurement of red blood cells, which led to the term, “Price-Jones curve”. See also his book, Red blood cell diameters, London, 1933.

1911 –1912

#902

The role of antithrombin and thromboplastin (thromboplastic substance) in the coagulation of blood.

1915

#903

A method for the determination of plasma and blood volume.

Keith, Rowntree, and Geraghty devised a method for determination of plasma and blood volume, which includes the injection of a dye.

1916

#904

The thromboplastic action of cephalin.

McLean extracted from dog liver a substance which retarded blood coagulation in vitro and which, after further work by Howell and Holt (No.905), was named heparin.

1918 –1919

#905

Two new factors in blood coagulation — heparin and pro-antithrombin.

Isolation of heparin.

1919

#906

Morphologische Hämatologie. Vol. 1.

1923

#907

L’hématoblaste, troisiéme élement du sang.

Hayem first named the hematoblasts in 1877 (Mém. Soc. Biol. (Paris), 1877, 29, 97). His view, reiterated in 1923, was that they were the early stages of red blood cells and regenerated the blood.

1924

#908

Relation of blood cells to connective tissues and endothelium.

Maximow’s blood regeneration theory.

1925

#909

Experimental studies on the origin and maturation of avian and mammalian red blood-cells.

1927

#910

A new agglutinable factor differentiating individual human bloods.

Discovery of M and N agglutinogens. See also the same journal, pp. 941-42.

1936

#911

Über spontane Hämolysinbildung im Blut, unter besonderer Berücksichtigung der Physiologie der Milz.

Lysolechtin found in normal blood.

1939

#912

Blood groups.

Boyd showed that blood groups are inherited and not changed by environment.

1947

#913

A new human iso-agglutinin subdividing the MN blood groups.

S blood-group antigen.

1660

#914

New experiments physico-mechanical touching the spring of the air.

Boyle showed the effects of the elasticity, compressibility, and weight of air. He investigated the function of air in respiration, combustion, and conveyance of sound. Most significantly Boyle demonstrated that air i…

1667

#916

An account of an experiment of preserving animals alive by blowing through their lungs with bellows.

By blowing air from a bellows over the exposed lungs of a dog, Hooke proved that respiratory motion is not necessary to maintain life, but that the essential feature of respiration lies in certain blood changes in the…

1746 –1747

#917

De respiratione experimenta anatomica, quibus aëris inter pulmonem etpleuram absentia demonstratur et musculorum intercostalium internorum officium adseritur. 2 pts.

First investigation of the action of the intercostal muscles in respiration.

1727

#918

De respirationis mechanismo atque usu genuino. [Praeses:] Georgius Erh. Hamberger. [Defendet:] Justinus Gerhardus Duising.

"Recent data on intercostal muscle function, largely electromyographic, tend to confirm the ideas of Hamberger, who, in 1748 (recte 1727), proposed a theory of intercostals muscle action upon the rib cage. Hamberger's…

1754

#919

Dissertatio medica inauguralis de humore acido a cibis orto, et magnesia alba.

Isolation of carbon dioxide. English translation, Minneapolis, 1973.

1772

#920

Observations on the different kinds of air.

The isolation of oxygen was first achieved by Priestley. He also demonstrated that plants immersed in water give off oxygen and that this gas is essential for animal life.

1772

#921

De aëre fixo dicto, aut mephitico.

Discovery of nitrogen.

1778

#922

Mémoire sur la nature du principe qui se combine avec les métaux pendantleur calcination, et qui en augmente le poids.

Although Priestley isolated oxygen, it was Lavoisier who discovered its real significance. He showed the true nature of the interchange of gases in the lungs and exploded Stahl’s phlogiston theory. Lavoisier was guill…

1784

#923

Mémoire sur la formation de l’acide, nommé air fixe ou acide crayeux, et que je désignerai désormais sous le nom d’acid du charbon.

1785

#924

Mémoire sur l’affinité du principe oxygine avec les différentes substances auxquelles il est susceptible de s’unir.

1784

#925

Experiments on air.

Cavendish isolated hydrogen in 1766, and later demonstrated the composition of air.

1791

#926

Mémoire sur la combinaison de l’oxigéne avec le carbone et l’hydrogéne du sang, sur la dissolution de l’oxigéne dans le sang, et sur la maniére dont le calorique se dégage.

Hassenfratz, a pupil of Lagrange, maintained that the oxidation of carbon and hydrogen took place in the blood, and not in the lungs as taught by others.

1808

#927

Über den Bau der Lungen.

In 1804 the Berlin Akademie der Naturwissenschaften offered a prize for the best essay on the structure and function of the lungs. The prize was won by Reisseisen, while Soemmerring received honorable mention. The tex…

1837

#929

Ueber die im Blute enthaltenen Gase, Sauerstoffe, Stickstoff, und Kohlensäure.

First quantitative analysis of the blood gases. Magnus proved that the arterial blood contains a higher concentration of oxygen than venous blood and that the latter had a higher carbon dioxide content.

1846

#930

On the capacity of the lungs, and on the respiratory functions, with a view of establishing a precise and easy method of detecting disease by the spirometer.

Invention of the spirometer, making possible the determination of the vital capacity of the lungs. Hutchinson used the spirometer while evaluating candidates for life insurance as a physician for Brittania Life. Parti…

1847

#931

Die Ursache der Lungenveränderung nach Durchschneidung der pneumogastrischen Nerven.

Study of the effect of section of the vagus on respiration. See also No. 933.

1849

#932

Recherches chimiques sur la respiration des animaux des diverses classes.

First determination of the respiratory quotient.

1850

#933

Ueber den Einfluss der Vagusdurchschneidung auf das Lungengewebe.

See No. 931.

1857

#934

Die Gase des Blutes.

Meyer showed that the oxygen in the blood was not held in simple solution but came off in quantity only when the air pressure was reduced to one fiftieth of an atmosphere.

1858

#935

De sanguine oxydo carbonico infesto.

Investigation of the blood gases.

1862

#936

Untersuchungen über den Bau der Nasenschleimhaut, namentlich die Structur und Endigungsweise der Geruchsnerven bei dem Menschen und den Wirbelthieren.

Schultze’s classic paper on the nerves to the neuro-epithelium in the special sense organs marks an epoch in histology. He described the cells of the olfactory muccous membrane, “Schultze’s cells”.

1862 –1863

#937

Ueber die Respiration.

1862 –1863

#938

Untersuchungen über die Respiration.

The first combined feeding–respiration experiments. Pettenkofer and Voit devised an apparatus for their important experiments on respiration and metabolism. They were first to estimate the amounts of protein, fat, and…

1866

#939

Zur Gasometrie des Blutes.

Pflüger showed that respiratory changes take place in the tissues.

1868

#940

Ueber die Ursache der Athembewegungen, sowie der Dyspnoë und Apnoë.

Pflüger investigated the cause of the initiation of respiration in newborn animals. English translation in No. 1588.16.

1868

#941

Die Selbststeuerung der Athmung durch den Nervus vagus.

1868

#942

Die Selbststeuerung der Athmung durch den Nervus vagus.

“Hering-Breuer reflex”; see also the previous entry. English translation of both papers in R. Porter (ed.), Hering–Breuer Centenary Symposium, London, Churchill, 1970. Digital facsimile of the 1868 edition from the Ba…

1871

#943

Der Kehlkopf des Menschen.

1878

#944

La pression barométrique. Recherches de physiologie expérimentale.

The most famous work in the history of altitude physiology, in which Bert proved that the principal symptoms of altitude sickness arise from reduced partial pressure of oxygen and not from diminution of total pressure…

1879 –1880

#945

On the respiratory function of the internal intercostal muscles.

The important work of Martin and Hartwell on the intercostal muscles settled the controversy regarding their function.

1882 –1892

#946

Normale und pathologische Anatomie der Nasenhöhle und ihrer pneumatischen Anhänge.

1889

#947

On the regulation of respiration.

Demonstration of the action of the vagus in respiration.

1894

#949

Neue Versuche zur Bestimmung der Sauerstoffcapacität des Blutfarbstoffs.

Hüfner showed that 1 gm. hemoglobin combines with 1.34 cc oxygen.

1897

#950

Fisiologia dell’uomo sulle Alpi. Studii fatti sul Monte Rosa.

Mosso made important investigations on respiration at high altitudes. He considered that the respiratory symptoms produced at high altitudes were due to lack of carbon dioxide. English translation, London, 1898.

1898

#951

A contribution to the chemistry of haemoglobin and its immediate derivatives.

Potassium ferricyanide method for the determination of oxygen in oxyhemoglobin.