Entry Nos. 4700–4799

1672

#1544

De anima brutorum

Chap. XIV is devoted to the sense of hearing; in it Willis described the “paracusis of Willis” (p. 73). English translation, 1683. A probable description of myasthenia gravis is given in Pars. 2, Cap. IX. In Pars 2, C…

1884

#3128

Ueber progressive perniciöse Anämie bei Tabeskranken

First description of subacute combined degeneration of the spinal cord, which Leichtenstern termed progressive pernicious anemia in tabetics.

1853

#4329

On the nature and treatment of the deformities of the human frame.

Little was the first eminent orthopedic surgeon in the British Isles. He studied under Stromeyer and, in 1838, he founded the Orthopaedic Institution, now the (Royal) National Orthopaedic Hospital, London. The above w…

1868

#4337

Sur quelques arthropathies qui paraissent dépendre d’une lésion du cerveau ou de la moëlle épinière.

Charcot called attention to tabetic arthropathy, a condition which has since borne his name, while the tabetic joints he so well described are now known as “Charcot’s joints”.

1886 –1888

#4569

A manual of diseases of the nervous system. 2 vols.

Gowers was physician and Professor of Clinical Medicine at University College, London. He especially distinguished himself in the field of neurology, and the above set is his greatest work.Page 365 of vol. 1 includes …

1880

#4700

Contribution à l’étude de l’idiotàie.

“Bourneville’s disease”, tuberous sclerosis, epiloia (p. 81). Digital facsimile from biuSante.parisdescartes.fr at this link. For the history of the understanding of this disease see the remarkable Wikipedia Timeline …

1883

#4701

De la parésie analgésique à panaris des extrémités supérieures ou paréso-analgésie des extrémités supérieures.

First description of “Morvan’s disease” – a form of syringomyelia.

1883

#4702

Ueber eine dem Bilde der cerebrospinalen grauen Degeneration ähnliche Erkrankung des centralen Nervensystems ohne anatomischen Befund, nebst einigen Bemerkungen über paradoxe Contraction.

“Westphal’s pseudosclerosis”. Later Strümpell’s description of this condition (No. 4709) led to the eponym “Westphal–Strumpell disease”.

1885

#4703

Über eine eigentümliche Form spastischer Lähmung mit Cerebralerscheinungen auf hereditärer Grundlage. (Multiple Sklerose.)

“Pelizaeus–Merzbacher disease” (see No. 4715).

1886

#4704

Ueber eine bestimmte Form der primären combinirten Systemerkrankungen des Rückenmarks.

“Strümpell’s disease” – hereditary spastic spinal paralysis, previously described by Erb and by Charcot.

1887

#4705

On arrested cerebral development, with special reference to its cortical pathology.

Sachs described the cerebral changes in amaurotic familial idiocy. Earlier, Tay (No. 5918) had recorded the ocular manifestations of this condition, which became known as “Tay-Sachs’s disease”. Two further papers on t…

1888

#4706

Ueber die Diagnose der Syringomyelie.

First complete description of syringomyelia.

1892

#4707

Ueber die Beziehungen der senilen Hirnatrophie zur Aphasie.

“Pick’s disease” – circumscribed atrophy of the brain with the development of aphasia and presenile dementia.

1892

#4708

A case of complete athetosis with post-mortem.

One of the earliest accounts of bilateral athetosis (“Vogt syndrome”, No. 4720).

1898

#4709

Ueber die Westphal’sche Pseudosklerose und über diffuse Hirnsklerose, insbesondere bei Kindem.

“Westphal-Strümpell disease” – pseudosclerosis of the brain. (See also No. 4702.) Probably cases of Kinnier Wilson’s disease.

1900

#4710

Subacute combined degeneration of the spinal cord.

First full description. Order of authorship in the original publication: Russell, Batten, Collier.

1900

#4711

A case of unilateral progressive ascending paralysis, probably representing a new form of degenerative disease.

First description of unilateral progressive ascending paralysis (“Mills’s disease”).

1903

#4712

Cerebral degeneration with symmetrical changes in the maculae in two members of a family.

Batten disease, a fatal disease of the nervous system that typically begins in childhood. Onset of symptoms is usually between 5 and 10 years of age. Often, it is autosomal recessive. It is the common name for a group…

1904

#4713

Cerebral degeneration, with symmetrical changes in the maculae, in three members of a family.

“Batten-Mayou disease”, juvenile amaurotic idiocy (see also No. 4712).

1906

#4714

Unilateral ascending paralysis and unilateral descending paralysis.

First description of unilateral descending paralysis.

1908

#4715

Weitere Mitteilungen über eine eigenartige hereditär-familiare Erkrankung des Zentralnervensystems.

“Pelizaeus-Merzbacher disease”, familial centrolobar sclerosis (see also No. 4703).

1908

#4716

Eine eigentümliche tonische Krampfform mit hysterischen Symptomen.

First description of torsion-spasm, dystonia musculorum deformans; also called “Ziehen–Oppenheim disease” following reports of cases by these writers in Neurol. Zbl., 1911, 30, 109, 1090.

1912

#4717

Progressive lenticular degeneration, a familial nervous disease associated with cirrhosis of the liver.

Classic description of progressive familial hepatolenticular degeneration (“Wilson’s disease”), first described by Frerichs in 1861 (see No. 4693), now considered to be a disorder of copper and ceruloplasmin metabolism.

1916

#4718

The histology of disseminated sclerosis.

A classic monograph on the pathology of multiple sclerosis.

1916

#4719

Le syndrome nerveux de l’espace rétro-parotidien postérieur.

“Villaret’s syndrome”.

1920

#4720

Zur Lehre der Erkrankungen des striären Systems.

“Vogt syndrome”, disease of the corpora striata.

1920

#4721

Les lésions anatomiques de la maladie de Parkinson.

Foix and his colleagues showed that the specific lesion in Parkinson’s disease is in the substantia nigra of the mid-brain.

1921

#4722

Ueber eigenartige Erkrankungen der Zentralnervensystems mit bemerkenswertem anatomischem Befunde. (Spastische Pseudosklerose — Encephalomyclopathie mit disseminirrten Degenerationsherden.)

“Creutzfeld-Jakob disease”, spastic pseudosclerosis. Traditionally considered to have been independently discovered by Creutzfeld, but in the 21st century recognized as a discovery by Jakob alone. See also No. 4719.1.

1921

#4723

Rapport sur les syndromes parkinsoniens.

Souques recognized the importance of encephalitis lethargica as a cause of Parkinsonism; more than any other neurologist he was responsible for unifying its diverse manifestations.

1922

#4724

Eigenartige Erkrankung in extrapyramidalen System mit besonderer Beteiligung des Globus pallidus und der Substantia nigra.

The (extrapyramidal) syndrome of Hallervorden and Spatz.

1936

#4725

Contribution à l’étude des syndromes du globe pâle. La dégénérescence progressive du globe pâle et de la portion réticuléé de la substance noire (maladie d’Hallervorden–Spatz).

Clovis Vincent, a pioneer French neurosurgeon, contributed a valuable study of Hallervorden–Spatz disease.

1946

#4726

Ueber Parpanit, einen neuen estrapyramidal-motorische Störungen beeinflussenden Stoff.

Introduction of caramiphen (“parpanit”) in the treatment of Parkinson’s disease.

1946

#4727

Le traitement de la maladie de Parkinson par le chlorhydrate de diéthylaminoéthyl-N-thiodiphénylamine (2987 R.P.). Premiers résultats.

Introduction of “diparcol” in the treatment of Parkinson’s disease. With D. Boyet and G. Dumont.

1949

#4728

Un nouveau médicament symptomatique des syndromes parkinsoniens: le chlorhydrate de [(diéthylamino-2’-methyl-2’) éthyl-1-’] N-dibenzoparathiazine.

Introduction of ethopropazine (“lysivane”) in the treatment of Parkinson’s disease.

1949

#4729

Trihexyphenidyl. Evaluation of the new agent in the treatment of parkinsonism.

Clinical introduction of benzhexol (“artane”) in Parkinson’s disease.

1740

#4731

A case of extraordinary exostoses on the back of a boy.

Probably the earliest description of myositis ossificans progressiva. Freke was a friend of Fielding, who mentioned him in Tom Jones.

1849

#4732

Recherches faites à l’aide du galvanisme sur l’état de la contractilité et de la sensibilité électro-musculaires dans les paralysies des membres superieures.

“Aran–Duchenne disease”, progressive muscular atrophy, with which the name of Cruveilhier is also associated. A fuller account is included in Duchenne’s Électrisation localisée, 1861, 437-547.

1850

#4733

Recherches sur une maladie non encore décrite du système musculaire. (Atrophie musculaire progressive).

“Aran–Duchenne disease” (see No. 4732)

1852 –1853

#4734

Sur la paralysie musculaire, progressive, atrophique.

“Cruveilhier’s palsy”, the progressive muscular atrophy already described by Duchenne and Aran. The slimness of the anterior roots was first noticed by Cruveilhier and was thought to be the essential lesion until Luys…

1860

#4736

Paralysie musculaire progressive de la langue, du voile du palais et des lévres; affection non encore décrite comme espèce morbide distincte.

First description of chronic progressive bulbar paralysis (“Duchenne’s paralysis”).

1860

#4737

Atrophie musculaire progressive. Lésions histologiques de la substance grise de la moëlle épinière.

Luys was the first to note the degeneration of the anterior horn cells in progressive muscular atrophy.

1865

#4738

Ueber Muskelhypertrophie.

Progressive muscular dystrophy with pseudo-hypertrophy. From the description given later by Duchenne (No. 4739) the condition has been named “Duchenne-Griesinger disease”.

1868

#4739

Recherches sur la paralysie musculaire pseudo-hypertrophique, ou paralysie myo-sclérosique.

“Duchenne muscular dystrophy”. English translation of first portion in Bick, Classics of orthopaedics, 72-75.

1869

#4740

Deux cas d’atrophie musculaire progressive avec lésions de la substance grise et des faisceaux antéro-latéraux de la moëlle épinière.

Description of the lesions of the spinal cord in muscular atrophy.

1869

#4741

Ueber Myositis ossificans progressiva.

Münchmeyer described a form of progressive ossifying myositis (“Münchmeyer’s disease”).

1874

#4742

Des amyotrophies spinales chroniques.

Charcot differentiated between the ordinary (Aran–Duchenne) type of muscular atrophy and the rarer amyotrophic lateral sclerosis, (ALS), at one time called “Charcot’s disease,” but more frequently designated today as …

1875 –1876

#4743

Klinik der Rückenmarks-Krankheiten. Bd. 2, pt.2.

First description of myotonia congenita occurs on p. 550.

1876

#4744

Tonische Krämpfe in willkürlich beweglichen Muskeln in Folge von ererbter psychischer Disposition (Ataxia muscularis?).

Thomsen suffered from muscle weakness and cramps, an issue that all his sons inherited. Realizing that this was a hereditary disease, Thomsen managed to trace the disease for six generations, and found over 20 cases o…

1877

#4745

On cerebritis, hysteria, and bulbar paralysis, as illustrative of arrest of function of the cerebro-spinal centres.

The case of “bulbar paralysis” (pp. 45-55) is believed to be the first definite record of myasthenia gravis.

1879

#4746

Ueber einen eigenthümlichen bulbären (?) Symptomenkomplex.

Myasthenia gravis (“Erb-Goldflam disease”; see also No. 4757). A further paper on the subject by Erb appears in the above volume, pp. 325-50.