Entry Nos. 3100–3199

1856

#22

Тα ∑ωζομενα. The extant works of Aretaeus, the Cappadocian. Edited and translated by Francis Adams.

Aretaeus left many fine descriptions of disease; in fact Garrison ranks him second only to Hippocrates in this respect. In the printed editions of this bibliography, before the present online version, the Adams editio…

1684

#1311

Dr. Willis's practice of physick.

The only complete edition of Willis's works in English, translated by the poet Samuel Pordage. It contains the translations of all his works except his Affectionum quae dicuntur hystericae (1671). The collection inclu…

1923 –1924

#2573.2

The soluble specific substance of pneumococcus.

Heidelberger, Avery, and their colleagues made a chemical study of the antigenic constituents of the pneumococcus, separating the polysaccharide antigens.

1941

#3100

The rôle of iso-immunization in the pathogenesis of erythroblastosis fetalis.

Erythroblastosis fetalis due to rhesus incompatibility (Rh disease) between mother and child. With L. Burnham, E. M. Katzin, and P. Vogel.

1941

#3102

Studies on the hemorrhagic sweet clover disease. V. Identification and synthesis of the hemorrhagic agent.

Isolation of dicoumarol (3:3-methylene-bis-4-hydroxycoumarin). With C. F. Huebner.

1945

#3103

Cyanosis in infants caused by nitrates in well water.

Methemoglobinemia. Comly first suggested the above hypothesis, since proved valid.

1945

#3104

Detection of weak and “incomplete” Rh agglutinins: a new test.

Coombs’s test for detecting antibodies in various clinical scenarios, such as Rh disease and blood transfusion. With A. E. Mourant and R. R. Race. A fuller description appears in Brit. J. exp. Path.,1945, 26, 255-66.

1945

#3105

Conglutination test for Rh sensitization.

Conglutination test.

1946

#3106

Leukaemia treated with urethane compared with deep x-ray therapy.

Urethane in treatment of leukemia. With A. Haddow, I. Ap Thomas, and J. M. Watkinson.

1947

#3107

Action hypoprothrombinémiante (anti-K) de la phényl-indanedione étudiée expérimentalement chez le lapin. Son application chez l’homme.

Introduction of phenylindanedione.

1948

#3108

Klinische Erfahrungen mit einem neuen Präparat der Cumarinreihe.

Introduction of ethyl biscoumacetate (“tromexan”).

1554

#3109

Medicinalium epistolarum miscellanea.

Epistle xxi, pp. 74-77, contains the first definite description of chlorosis. “De morbo virgineo”. English translation in No. 2241.

1731

#3110

Godofredus Augustus Emmrich: Disseratione inauguralis De genuina chlorosis indole, origine et curatione. Von der wahren Eigenschaft, Ursprung und Cur der Bleichsucht.

Classic description of chlorosis. Lange accurately diagnosed this condition, but it was left to Hoffmann to separate it as a definite entity. Hoffmann published his contribution to this subject in the thesis of his st…

1795

#3111

Hints respecting the chlorosis of boarding schools.

1824

#3112

History of a case of anaemia.

First description of pernicious anemia. Paper read May 1, 1822.

1832

#3113

Sur les maladies chlorotiques et sur un mode de traitement spécifique dans ces affections.

For the treatment of chlorosis Blaud prescribed a pill (Blaud’s pill) composed of sulphate of iron and carbonate of potassium. Preliminary report in Bull. gén. Thérap.,1832, 2,154-55.

1832

#3114

Die krankhafte Mischung des Blutes, vorzüglich bei Chlorose, Hysterie und Pneumonie, durch chemische Versuche ausgemittelt, und der Uebergang in den Darmcanal eingebrachten Eisens.

Foedisch showed chlorotic blood to be deficient in iron. See also Gaz. méd. Paris, 1837, 2 sér. 5,7.

1836

#3115

Das Blut in mehrfacher Beziehung physiologisch und pathologisch untersucht.

Nasse gave the first clear description of anemia in pregnancy; he also noticed erythrocyte sedimentation in certain pathological conditions.

1842

#3116

Notes on anhaemia, principally in its connections with the puerperal state, and with functional disease of the uterus: with cases.

First description of pernicious anemia of pregnancy. Digital facsimile from the U.S. National Library of Medicine at this link.

1847

#3117

Puerperal anaemia; or a peculiar anaemic condition, occurring in gestating and lactating females.

Bennett described the anemia of pregnancy and defined it as resulting from the process of reproduction.

1849

#3118

Anaemia; disease of the supra-renal capsules.

Addison included a classic description of pernicious (Addisonian) anemia in his papers on the condition later known as “Addison’s disease”. Although preceded by Combe, his account was more important in bringing the di…

1866

#3119

Ein Fall von Anaemia splenica bei einem Kinde

First reported case of (infantile) splenic anemia.

1867

#3120

Beiträge zur Pathologie und Therapie der Chlorose.

Duncan showed that the essential feature in chlorosis is a quantitative change in the hemoglobin content and not a great reduction in the number of red blood cells.

1870

#3121

Cachessia puerperale raccolta nella clinica ginecologica dell’ospitale Maggiore di Milano.

“Valsuani’s disease” – progressive anemia in pregnant and lactating women, probably first described by H. N. Bennett (No. 3117).

1871

#3122

Ueber hochgradigste Anämie Schwangerer.

An important account of pernicious anemia of pregnancy.

1872

#3124

Eine eigenthumliche Form von progressiver perniciöser Anämie.

In his account of progressive pernicious anemia, Biermer was first to describe the retinal haemorrhages. He was at one time accredited with the first description of pernicious anemia ; later it was shown that Addison …

1875

#3125

Progressive pernicious anaemia, or anaematosis.

Pepper described bone-marrow changes of pernicious anemia, though his actual description more closely resembles leukaemia.

1882

#3126

Dell’anemia splenica.

“Banti’s disease”. Banti described the pathological changes in the spleen in splenic anemia. A later paper in Sperimentale, 1894, 48, sez. biol., 407-32, gives an account of hepatic cirrhosis as the sequel of the earl…

1882

#3127

De l’epithélioma primitif de la rate; hypertrophie idiopathique de la rate sans leucémie.

“Gaucher’s disease” – familial splenic anemia. Digital facsimile from wellcomecollection.org at this link.

1884

#3128

Ueber progressive perniciöse Anämie bei Tabeskranken

First description of subacute combined degeneration of the spinal cord, which Leichtenstern termed progressive pernicious anemia in tabetics.

1888

#3129

Ueber einen Fall von Anämie mit Bemerkungen über regenerative Veränderungen des Knochenmarks.

Ehrlich was first to distinguish the aplastic type of anemia.

1889

#3130

Du sang et de ses altérations anatomiques

Includes (pp. 614-751) an important account of chlorosis; Hayem, by his accurate observation, placed knowledge of the disease on a firm basis.

1889

#3131

Ueber Leukaemia und Leukocytose im Kindesalter.

From this classic description of infantile pseudoleukemic anemia, the condition became known as “von Jaksch’s disease”.

1895

#3132

Ueber die Eisentherapie.

Bunge was father to the concept of iron-deficiency anemia.

1910

#3133

Peculiar elongated and sickle-shaped red blood corpuscles in a case of severe anemia.

Identification of the sickle-cell type of anemia. Abstract "This case is reported because of the unusual blood findings, no duplicate of which I have ever seen described. Whether the blood picture represents merely a …

1913

#3134

Anämische Zustände bei der chronischen Achylia gastrica.

Simple achlorhydric (idiopathic microcytic) anemia described. Faber advanced the view that achylia gastrica was a cause both of pernicious anemia and of simple chlorotic anemia.

1918

#3135

A clinical study of puerperal anaemia.

Four cases of pernicious anemia of pregnancy treated by blood transfusion.

1919

#3136

Observations on the severe anaemias of pregnancy and the post-partum state.

Osler described his four-part classification of anemias of pregnancy: anemia from post-partum hemorrhage, severe anemia of pregnancy, post-partum anemia, and the acute anemia of post-partum sepsis. This was Osler's la…

1925

#3137

Ueber Anaemia infectiosa chronica und ihre Aetiologie.

“Edelmann’s disease” – a type of chronic infectious anemia.

1925

#3138

A form of acute hemolytic anemia probably of infectious origin.

“Lederer’s anemia” first described.

1925

#3139

Blood regeneration in severe anaemia. II. Favourable influence of liver, heart and skeletal muscle in diet.

These workers showed the beneficial effect of raw beef liver upon blood regeneration in anemia. Their work paved the way for the liver diet treatment of Minot and Murphy. In 1934 Whipple shared the Nobel Prize in Phys…

1926

#3140

Treatment of pernicious anemia by a special diet.

Introduction of raw liver diet in the treatment of pernicious anemia. This treatment ranks as one of the greatest modern advances in therapy. See also the later paper in the same journal, 1927, 89,759-66. Reprinted in…

1927

#3141

Anemia in children, with splenomegaly and peculiar changes in the bones.

“Cooley’s erythroblastic anemia”, thalassemia. With E. R. Witwer and O. P. Lee. An earlier brief account by Cooley and Lee appeared in Trans. Amer. Pediat. Soc.,1925, 37, 29.

1927

#3142

Familiäre infantile perniziösaartige Anämie (perniziöses Blutbild und Konstitution).

“Fanconi’s syndrome”, congenital hypoplasia of bone marrow with multiple congenital defects occurring as a familial disease.

1929

#3143

Observations on the etiologic relationship of achylia gastrica to pernicious anemia. I. The effect of the administration to patients with pernicious anemia of the contents of the normal human stomach recovered after the ingestion of beef muscle.

Castle showed pernicious anemia to be due to absence from the gastric juice of a substance (Castle’s intrinsic factor, hemopoietin) that reacts with an extrinsic factor present in many foodstuffs to form the anti-pern…

1929

#3144

Desiccated stomach in the treatment of pernicious anemia.

Sturgis and Isaacs showed that stomach tissue contains a factor active in the treatment of pernicious anemia.

1930

#3145

Classification of the anemias on the basis of differences in the size and hemoglobin content of the red corpuscles.

Wintrobe’s classification of the anemias.

1931

#3146

Treatment of “pernicious anaemia of pregnancy” and “tropical anaemia”, with special reference to yeast extract as a curative agent.

First observations of hemopoietic effect of folic acid.

1932

#3147

The classification and treatment of anaemia, with special reference to the nutritional factor.

Davidson’s classification of the anemias.

1935

#3148

Achresthic anaemia.

Achrestic anemia described.