HOWELL, William Henry (1860 – 1945)

1890 –1891

#886

The life history of the formed elements of the blood, especially the red blood corpuscles.

Includes description of “Howell’s bodies” seen in mature erythrocytes and called also “Howell–Jolly bodies” after the later description by J. M. J. Jolly.

1905 –1906

#1337

Vagus inhibition of the heart in its relation to the inorganic salts of the blood.

Howell suggested that nerve impulses act indirectly by increasing the amount of diffusible potassium compounds in the heart tissue.

1906

#730.1

Note upon the presence of amino-acids in the blood and lymph as determined by the ß naphthalinsulphochloride reaction.

Demonstration of the presence of amino-acids in the blood.

1910

#899

The preparation and properties of thrombin, together with observations on antithrombin and prothrombin.

1911 –1912

#902

The role of antithrombin and thromboplastin (thromboplastic substance) in the coagulation of blood.

1918 –1919

#905

Two new factors in blood coagulation — heparin and pro-antithrombin.

Isolation of heparin.