1920–1929

1924

#530

Über Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren.

This was Hilde Mangold's thesis. Spemann designed the experiment, and Mangold performed the work, and was the co-discoverer of the "organizer," the chemical that directs the embryonic development of tissues and organs…

1924

#748

Chemical dynamics of life phenomena.

1924

#747

Studies in nuclein metabolism. II. The isolation of a nucleotide from human blood.

Jackson demonstrated the existence of pentose nucleotides in normal blood.

1924

#1787

The Assyrian herbal: A monograph on the Assyrian vegetable drugs, the subject matter of which was communicated in a paper to the Royal Society, March 20, 1924.

A study of Assyrian material medical reproduced by cyclostyle, in the author's handwriting.

1924

#1238

A description of the glomerular circulation in the frog’s kidney and observations concerning the action of adrenalin and various other substances upon it.

Richards made many experiments concerning the secretion of urine. Among other things he collected and analysed the fluid from a single glomerulus; his work confirmed the theories of Ludwig and Cushny.

1924

#1239

Observations on the composition of glomerular urine with particular reference to the problem of reabsorption in the renal tubules.

Experimental proof that the initial step in urine production is the formation in Bowman’s space of a protein-free ultrafiltrate of plasma and that reabsorption of certain substances must occur in the tubules since the…

1924 –1925

#1240

The secretion of urine as studied on the isolated kidney.

Demonstration that the anti-diuretic action of vasopressin is exerted directly on the kidney, and that tubules of the kidney reabsorb water.

1924

#1442

Experimental researches on sensory localization in the cerebral cortex of the monkey (Macacus).

Dusser de Barenne demonstrated the major functional subdivisions of the sensory cortex.

1924

#1443

Reflexes in response to stretch (myotatic reflexes).

This investigation of the stretch reflex was of value in elucidating muscle tone and posture.

1924

#139

Regeneration from a physico-chemical viewpoint.

1924 –1925

#2049

Malati medici e farmacisti: Storia dei rimedi traverso i secoli e delle teorie che ne spiegano l’azione sull’organismo. 2 vols.

Second edition, 1947-51.

1924

#2086

Phantastica.

The classic of psychoactive drug classification. Lewin established the following categories: Euphorics, Phantastics, Inebriants, Hypnotics, and Excitants. English translation, 1931.

1924

#2440.1

A plea for the early recognition of leprosy, with notes on diagnosis and methods.

The scraped-incision slit-skin method for bacterial examination in leprosy.

1924

#2602

Vascular reactions of the skin to injury. II. The liberation of a histamine-like substance in injured skin; the underlying cause of factitious urticaria and of wheals produced by burning; and observations upon the nervous control of certain skin reactions.

Lewis postulated that a histamine-like substance (“H-substance”) was responsible for the anaphylaxis symptom-complex. See also The blood-vessels of the human skin and their responses, 1927 (No. 797).

1924

#2343

Essai d’immunisation contre l’infection tuberculeuse.

B.C.G. (Bacille Calmette–Guérin) vaccine was first produced in 1906 and subcultured for 13 years. It was first used as a prophylactic against tuberculosis in children in 1921. It remains in use. See also No. 2346.

1924

#1758

The doctor’s oath, an essay in the history of medicine.

The Hippocratic Oath forms the basis of medical ethics. It was probably an ancient temple oath of the Asclepiadae, and not a genuine Hippocratic document. In the above work the various manuscripts of the Oath are enum…

1924

#1766.603

The medical sciences in the German Universities: a study in the history of civilization. Translated by William H. Welch.

German edition first published in 1876.

1924

#2646

The formation of a cancer-producing substance from isoprene (2-methyl-butadiene).

Kennaway produced carcinogenic tars by submitting acetylene or isoprene to high temperatures in an atmosphere of hydrogen, thus proving that some carcinogens are pure hydrocarbons.

1924

#2854

Rheumatic heart disease.

The first systematic textbook on rheumatic heart disease.

1924

#2855

A hitherto undescribed form of valvular and mural endocarditis.

“Libman–Sacks disease”.

1924

#2573.1

The genetics of tissue transplantation in mammals.

Little established that the homograft reaction was due to genetic differences between donor and recipient.

1924

#3199

L’exploration radiologique des cavités broncho-pulmonaires par les injections intra-trachéales d’huile iodée.

Bronchography was advanced by the work of Sicard and Forestier on the intratracheal introduction of lipiodol.

1924

#3324

Technic of a pan-sinus operation.

Independently of Howarth (No. 3322), Lynch devised an operation for the conservative treatment of sinusitis.

1924

#3652

Roentgenologic examination of the gallbladder.

Introduction of cholecystography.

1924

#3653

Studies in hepatic function. VI. A. The pharmacological behavior of certain dyes. B. The value of selected phthalein compounds in the estimation of hepatic function.

Bromsulphthalein test for liver function.

1924

#3851

The value of iodine in exophthalmic goitre.

Plummer and Boothby recommended the pre-operative administration of iodine in exophthalmic goitre.

1924

#2916.1

Intra-arterial injection of sodium iodide: Preliminary report.

Clinical angiography.

1924

#2916.2

A clinical study of diseases of the circulation of the extremities; a description of a new method of examination.

Femoral arteriography.

1924

#4244

An unexplained diazo-colour-reaction in uraemic sera.

Diazo-color test of renal function.

1924 –1933

#3405

Atlas of otology illustrating the normal and pathological anatomy of the temporal bone. 2 vols.

1924

#3405.1

Binaural minimum audition in a subject with ranges of deficient acuity.

First demonstration of the phenomenon of loudness recruitment.

1924

#3970

Insulin.

1924

#3016

Ein durch die Trendelenburgsche Operation geheilter Fall von Embolie der Art. pulmonalis.

First successful surgical treatment of pulmonary embolism, a procedure suggested by Trendelenburg in 1908 (see No. 3012).

1924

#4893

The influence of the sympathetic nervous system in the genesis of the rigidity of striated muscle in a spastic paralysis.

Hunter believed in the sympathetic innervation of skeletal muscle and on this assumption devised the technique of sympathetic ramisection carried out by Royle (No. 4894). Biography by M.J. Blunt, Sydney, 1985.

1924

#4894

A new operative procedure in the treatment of spastic paralysis and its experimental basis.

Sympathetic ramisection. See also Surg. Gynec. Obstet., 1924, 39, 701-20.

1924

#5069

Ueber cutane Hautreaktion mittels Diphtherie-Toxin zum Nachweis der Diphtherie-Immunität.

The “scratch test”, a cutaneous reaction for determination of susceptibility to diphtheria.

1924

#5082

A skin test for susceptibility to scarlet fever.

The “Dick test” for the determination of individual susceptibility to scarlet fever.

1924

#5082.1

The etiology of scarlet fever.

Proof that streptococcus is the cause of scarlet fever.

1924

#5083

A scarlet fever antitoxin.

Following their successful attempts to establish individual susceptibility to scarlet fever, these workers prepared an antitoxin for immunization.

1924

#5084

The significance of Streptococcus hemolyticus in scarlet fever and the preparation of a specific anti-scarlatinal serum by immunization of the horse to Streptococcus hemolyticus-scarlatinae.

Dochez and Sherman immunized a horse by repeated injections of scarlet fever toxin. A serum obtained from the horse blanched a scarlet fever rash and, when injected subcutaneously, caused marked amelioration of the ea…

1924

#4392

Hypertelorism. A hitherto undifferentiated congenital cranio-facial deformity.

First description of hypertelorism as a separate entity.

1924

#4392.1

The reconstruction operation for arthritis deformans of the hip-joint.

The first sustained attempt to relieve osteoarthrosis of the hip by surgical means other than fusion.

1924

#5301.1

On a Herpetomonas found in the gut of the sandfly, Phlebotomus argentipes, fed on kala-azar patients.

Demonstration that L. donovani is capable of reproduction in Phlebotomus. With R. O. Smith.

1924

#5327

Observations on the causal organism of rat-bite fever in man.

Robertson proved one of the causal organisms of rat-bite fever to be Sp. morsus muris. He re-named it Spirillum minus Carter, 1887, identifying it as the first spiral micro-organism to be described from a rodent.

1924 –1929

#6129

Biologie und Pathologie des Weibes. Hrsg. von 8 vols.

Second edition, 10 vols. & index, 1941-55.

1924

#6252

Césarienne suivie d’extériorisation temporaire de l’utérus et de réintégration secondaire dans le bassin.

Portes operation – the classic Caesarean section followed by temporary exteriorization of the uterus. More fully described in Gynéc. et Obstét., 1924, 10, 225-50.

1924

#6296

Geschichte der Gynäkologie. In: J. von Halban and L. Seitz: Biologie und Pathologie des Weibes.1, 1-202.

1924

#6512

Die Medizin im Avesta.

The Avesta (Persian: اوستا) is the primary collection of religious texts of Zoroastrianism, composed in the otherwise unrecorded Avestan language.

1924

#6350

The food requirements of malnourished infants with a note on the use of insulin.

Marriott introduced the insulin-fattening method of treatment of malnutrition in infants.

1924

#6372

Aleukämische Reticulose. (Ein Beitrag zu den proliferativen Erkrankungen des Retikuloendothelialapparates.)

“Letterer–Siwe disease”; see also No. 6373.