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1953

#14072

Induction of instability at selected loci in maize.

McClintock (Nobel Prize 1983) discovered transposable elements or jumping genes. She found that certain parts of chromosome had switched position. This refuted the then-popular theory that genes were fixed in their po…

1902

#14071

Historia de la medicina en Guatemala.

Digital facsimile from Google Books at this link. Second edition, 1958 with appendix listing physicians, surgeons and pharmacists who received degrees or taught at the University of Guatemala from1902 to 1953.

1986

#14070

Bibliography of publications in legal medicine & forensic sciences relating to Sri Lanka 1811 - 1984.

1963

#14069

On the aims and methods of ethology.

In this paper Tinbergen defined Tinbergen's Four Questions, or complementary categories of explanations for animal behavior. that form the basis of ethology: Causation, Ontogeny, Survival Value, and Evolution. In 1973…

2016

#14068

Influenza encyclopedia: The American influenza epidemic of 1918 - 1919: A digital encyclopedia. Second edition.

ABOUT "Historians, journalists, and the public at large have long been interested in the 1918 “Spanish flu” epidemic, a dramatic chapter in American life that has spawned an impressive body of books, articles, and mul…

2015

#14067

Evolution of Darwin’s finches and their beaks revealed by genome sequencing.

The authors sequenced the genome of 120 individuals representing all of Darwin’s finches. They found that a 240 kilobase haplotype encompassing the ALX1 gene, which encodes a transcription factor affecting craniofacia…

2006

#14066

Evolution of character displacement in Darwin’s finches.

Through their more than 40 year study of Darwin's finches on the Island of Daphne Major in the Galapagos, the Grants demonstrated how natural selection can drive rapid changes in body and beak size in response to chan…

1956

#14065

Character displacement.

In this paper Brown and Wilson defined character displacement as follows: "Two closely related species have overlapping ranges. In the parts of the ranges where one species occurs alone, the populations of that specie…

1966

#14064

"Fertile" intestine nuclei.

Gurdon and Uehlinger replaced the cell nucleus of frog ova with frog intestinal nuclei to generate tadpoles, some of which became fertile adult male and female frogs. In 2012 the Nobel Prize in Physiology or Medicine …

2007

#14063

Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Yamanaka (Nobel Prize 2012) and colleagues demonstrated the generation of Induced Pluripotent Stems Cells (iPS) from adult human dermal fibroblasts with the same 4 mice factors they used in GM 13287. By overexpressing…

1856

#14062

Kitab-i jarrahi wa yak risalah dar kahhali [in Persian; English translation: Book on surgery with a treatise on ophthalmology]. Lithographed text.

The first Persian-language surgery and ophthalmology textbook based on Western medical science. Polak based his textbook on Joseph Maximilien Chelius’s Handbuch der Chirurgie (1830) and Handbuch der Augenheilkunde (18…

1854

#14061

Kitab fi tashrih beden al-insan [in Persian; English translation: Anatomy of the human body]. Lithographed text.

The first original Persian-language anatomy textbook based on western medical science, printed in a very small number of copies for the use of Polak’s Persian students. Polak, an Austrian physician, was responsible fo…

1876

#14060

Explorations of the aboriginal remains of Tennessee.

The first major discussion of human skeletal pathology in American archeological samples. Jones introduced histopathological techniques in analysis of paleopathological material. Digital facsimile from Google Books at…

2022

#14059

Masters of health: Racial science and slavery in U.S. medical schools.

2021

#14058

Medicine and healing in the age of slavery. Edited by Sean Morey Smith & Christopher D. E. Willoughby.

1974

#14057

Pop goes the café coronary.

Heimlich proposed and described the eponymous “Heimlich maneuver” for what was then called the “café coronary,” a cause of sudden death seen mostly in restaurants, or at the dinner table, most often on those ingesting…

1959

#14056

Pheromones (ectohormones) in insects.

Karlson and Butenandt (Nobel Prize 1939) defined pheromones as “substances which are secreted to the outside by an individual of the same species, in which they release a specific reaction, for example, a definite beh…

1969

#14055

Preliminary examination of lunar samples from Apollo 11: A physical, chemical, mineralogical, and biological analysis of 22 kilograms of lunar rocks and fines.

On p. 1226 the massive number of authors reported that "microscopic, culture, injection and inoculation studies on many different organisms to include mice, fish, invertebrates, insects, plants and lower animals such …

1988

#14054

Tibetan medical thangka of the four medical tantras. Translator and compiler of the original edition: Byams-pa 'Phrin-Las, Wang lei. English translator and annotator Cai Jingfeng.

1939

#14053

A preliminary atlas of early human fetal activity.

The first published photographic study of fetal physiology using live human fetuses. Includes 20 full-age photographic plates, each with 6-12 images (189 total). The fetuses, all between 8.5 and 14 weeks gestation, we…

2022

#14052

The arsenal of eighteenth-century chemistry: The laboratories of Antoine Laurent Lavoisier (1743-1794) by Marco Beretta and Paolo Brenni.

"The substantial collection of Antoine Laurent Lavoisier’s apparatus is not the only surviving collection of eighteenth-century chemical apparatus and instrumentation, but it is without question the most important. Th…

1784

#14051

Abrégé historique des hopitaux, contenant leur origine, les différentes especes d’hopitaux, d’hospitaliers et hospitalieres, et les suppressions et changemens faits dans les hôpitaux, en France, par les édits et réglemens de nos rois .…

A history of hospitals in France from the earliest times, through charitable care for the poor by monks and nuns, to their evolution through legislation of the 16th and 17yh centuries. Includes a list of charitable in…

1996

#14050

The great pox. The French disease in Renaissance Europe.

2022

#14049

Climate change increases cross-species viral transmission risk.

1) Using a phylogeographical model of the mammal-virus network, and projections of geographical range shifts, the authors assert that 3,139 mammal species will aggregate in new combinations at high elevations, seeking…

2006

#14048

An inconvenient truth. The planetary emergency of global warming and what we can do about it.

A politician, Gore was one of the first to draw popular attention to climate change. He supplemented the best-selling book with a film and DVD with the same title. Ten years later, recognizing that in spite of its wid…

1864

#14047

The origin of human races and the antiquity of man deduced from the theory of “natural selection."

Wallace delivered this paper to the polygenist Anthropological Society of London on 1 March 1864. It represents “the first effort to connect natural selection to the touchy problem of the evolution of human races” (Wa…

1996

#14046

The lac Operon: A short history of a genetic paradigm.

1862

#14045

On the extent and aims of a national museum of natural history.

Owen was the prime mover behind the construction of the Natural History Museum, a project that occupied him for over two decades. His On the Extent and Aims of a National Museum of Natural History, containing the text…

1910

#14044

The orders of mammals. Part 1.- Typical stages in the history of the ordinal classification of mammals. Part II. - Genetic relations of the mammalian orders; with a discussion of the origin of the mammalia and of the problem of the auditory ossicles.

Gregory's PhD dissertation, of particular significance for its exhaustive analysis of prior taxonomic systems for mammalia. Digital facsimile from Google Books at this link.

2020

#14043

Patents on life: Religious, moral, and social justice aspects of biotechnology and intellectual property. Edited by Thomas C. Berg, Roman Cholij, and Simon Ravenscroft.

1864

#14042

The reputed fossil man of the Neanderthal.

King believed that the Feldhofer Neanderthal skull discovered by Fuhrott and Schaafhausen differed significantly from all known ancient and modern human crania. In this paper he proposed the name Homo neanderthalensis…

2006

#14041

Race and the odd history of human paleontology.

Abstract: "Although the late 17th century witnessed the recognition of fossils as the remains of extinct organisms—because they could be incorporated into the creation story embodied in the Great Chain of Being—accept…

2019

#14040

Deer Leibarzt des Schah Jacob E. Polak 1818-1891. Eine west-östliche Lebensgeschichte.

1883

#14039

Essai de géographie médicale de l'Ille Nosi-Bé près la cote nord-ouest de Madagascar (avec cartes). Thèse pour le doctorat en médicine.

1932

#14038

The process of tendon repair: An experimental study of tendon suture and tendon graft.

1865

#14037

Persien. Das Land und seine Bewohner. Ethnographische Schilderungen. 2 vols.

In this wide-ranging ethnographic study Polak provided the most authoritative account of his introduction of western medicine into Iran as well as the state of medicine in Iran generally. "Polak (1865, II, pp. 192-348…

1955

#14036

Old English silver and its medical interest. Presidential Address, Liverpool Medical Institution, 14th October 1954.

Digital facsimile from wellcomecollection.org at this link.

1965

#14035

The nature of the Negri Body.

The first visual proof, by publication of electron micrographs at 25,000 magnification, that Negri bodies contain enormous numbers of rabies virus particles. Digital facsimile from rupress.org at this link. (Thanks to…

1903

#14034

Le passage du virus rabique à travers les filtres.

By demonstrating that the rabies organism is filterable Remlinger proved that rabies is a virus. The rabies virus was the second virus causing disease in humans to be identified. Remlinger made his discovery by follow…

2004

#14033

Public health in Qajar Iran.

"Until Now, there have been no books and only a few articles available in English that deal with the actual practice of medicine in nineteenth and early twentieth-century Iran. Willem Floor’s Public Health in Qajar Ir…

2018

#14032

Studies in the history of medicine in Iran.

2020

#14031

The beginnings of modern medicine in Iran.

2021

#14030

History of hospitals in Iran, 550-1950.

2005

#14029

Body counts: Medical quantification in historical and sociological perspective / La quantificattion medicale, perspectives historiques et sociologigues. Edited by Gérard Jorland, Annick Opinel and George Weisz.

1882

#14028

Experimental physiology: Its benefits to mankind, with an address on unveiling the statue of William Harvey at Folkestone 6th August 1881.

A little-known historical work on the history of physiology and the history of medicine by Owen, who, even though he was trained in medicine, most often wrote on topics in comparative anatomy, zoology, paleontology an…

2022

#14027

AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models.

Abstract: "The AlphaFold Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk) is an openly accessible, extensive database of high-accuracy protein-structure predictions. Powered by AlphaFold v2.0 of …

2021

#14026

Highly accurate protein structure prediction with AlphaFold.

Abstract: "Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. Through an enormous experimental effort1,2,3,4, the structures of around 100,0…

1926

#14025

The isolation and crystallization of the enzyme urease.

Sumner first isolated and crystallized an enzyme (urease) and proved that enzymes are proteins. One month after publication of the above paper Sumner reinforced his discovery by recrystalizing urease, publishing a fol…

2014

#14024

A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits.

Free access from FEBS Press at this link.

2021

#14023

An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.

The authors showed how a coronavirus specific protease inhibitor designed in the lab, that could be administered by mouth to humans, achieved excellent plasma concentrations and antiviral potency. This drug, marketed …