Latest Entries
Recently added and updated annotations in the corpus.
2021
#14122
Augustin Cabanès (1862-1928): Clinicien de l'histoire ou vulgaire anecdotier?
1703
#14121
L'art de faire les raports en chirurgie, où l'on ensiegne la pratique, les formules & le stile le plus en usage parmi les chirurgiens commis aux rapports; avec un extrait des arrest, statuts & reglemens faits en consequence.
Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for this reference.)
1782
#14120
Unterricht für Krankenwärter zum Gebrauch öffentlicher Vorlesungen.
The first German book on nursing--a manual of instructions for male nurses. Digital facsimile from Google Books at this link. (Thanks for Webb Dordick for this reference.)
1786
#14119
Manuel pour le service des malades, ou précis des connoissances nécessaires aux personnes chargées du soin des malades, femmes en couche, enfans nouveaux-nés, &c.
The first French book on nursing. Digital facsimile of the 1787 edition from the Internet Archive at this link. (Thanks to Webb Dordick for this reference.)
1785
#14118
Catalogue raisonné des ouvrages qui ont été publiés sur les eaux minérales en général et sur celles de la France en particulier, avec un notice doutes des eaux minérales de ce royaume, et un tableau des différens degrés de température de celles qui son thermales.
The earliest bibliography of mineral springs. Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for this reference.)
1773
#14117
A treatise on the kinkcough. With an appendix. Containing an account of hemlock, and its preparation.
Probably the first book on whooping cough, proceeding Watt's book by 40 years. Butter proposed hemlock as a treatment for whooping cough. Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for t…
1987
#14116
Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (Leuko-Araiosis).
"Abstract: As part of a prospective clinicopathologic study, a cohort of 105 "normal" elderly volunteers was investigated with computed tomographic scans, psychometric testing (Extended Scale for Dementia [ESD]) and n…
1974
#14115
Multi-infarct dementia. A cause of mental deterioration in the elderly.
The authors showed that contrary to the prevailing view that most dementias were caused by hardened brain arteries (cerebral atherosclerosis), most were multi-infarct dementias—dementias caused by multiple, small, oft…
2012
#14114
Cardiovascular and neurological causes of sudden death after ischaemic stroke.
Hachinski and Sörös discovered that the control of the heart by the brain is asymmetric, with the fight/flight (sympathetic) response controlled by the right hemisphere and the rest and digest (parasympathetic) respon…
1485
#14113
De balneis et thermis naturalibus omnibus Italiae.
The second printed book on balneology. Savonarola took a skeptical approach to the subject, relying on his own observations and rejecting the notion that baths owed their virtues to occult or supernatural properties. …
2011
#14112
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
Carl H. June and colleagues proved that the ‘concept’ of CAR T-cell therapy developed by them, was a very promising and viable alternative in specific recalcitrant cancers. They showed that their novel in-vitro-create…
2001
#14111
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
The authors showed that the experimental drug (STI571) Imatinib, sold under the brand names Gleevec and Glivec, 1) was well tolerated and had very significant antileukemic activity in patients with chronic myeloid leu…
1938
#14110
Artificial fever produced by physical means; its development and application.
Perhaps the most comprehensive study of the application of pyrotherapy in the treatment of a wide variety of diseases, including syphilis. For syphilis in particular the treatment was replaced by penicillin, developed…
2002
#14109
La dermatologie en France. Edited by Daniel Wallach and Gérard Tilles
"Realisé à l'initiative de la Société française d'histoire de la dermatologie. Rédigé par 76 auteurs représentant la communauté dermatologique française, cet ouvrage constitue le cadeau officiel du vingtième Congrès m…
1980
#14108
The striking resemblance of high-resolution G-banded chromosomes of man and chimpanzee.
Chimpanzees are the closest primates genetically to humans. In this paper the authors demonstrated the genetic changes that differentiated humans from chimpanzees. By comparing human and chimpanzee chromosomes the aut…
2022
#14107
Genetics of atavism.
Abstract: "Atavisms have attracted people’s attention for a long time. First, atavisms excited their imagination and created fertile ground for myths and superstitions. With the development of science, atavisms became…
2022
#14106
Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models.
Abstract: "We evaluated the performance of a large language model called ChatGPT on the United States Medical Licensing Exam (USMLE), which consists of three exams: Step 1, Step 2CK, and Step 3. ChatGPT performed at o…
1835
#14105
Nouvelles recherches sur la structure de la peau.
Beschet emphasized "the relevance of anatomic investigation to dermatologic problems" (Crissey and Parish, Dermatology and syphilology of the nineteenth century, 117). In this book the authors first described the anat…
2021
#14104
Morbid undercurrents: Medical subcultures in postrevolutionary France.
"During the 1790s and beyond, medicine left the somber halls of universities, hospitals, and learned societies and became profoundly politicized, inspiring a whole panoply of different—often bizarre and shocking—subcu…
1963
#14103
Recurrent Dupuytren's contracture.
Hueston described Dupuytren's diathesis, including early onset, bilateral involvement, postive family history, and presence of ectopic lesions. He noted that patents presenting Dupuytren's diathesis experience more se…
2017
#14102
The role of the WI-38 cell strain in saving lives and reducing morbidity.
In 1961 "Hayflick developed the first normal human diploid cell strains for studies on human aging and for research use throughout the world. Prior to his seminal research, all cultured cell lines were immortal and an…
2013
#14101
The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.
Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…
1952
#14100
Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium.
A cell biologist at Johns Hopkins Hospital, Gey propagated the HeLa cell line from Henrietta Lacks' cervical tumor. This cell line, which maintained a continuous growth phase, was the first immortal human cell line to…
2018
#14099
The genome of the offspring of a Neanderthal mother and a Denisovan father.
Paleogenomic study of a single bone fragment from a female hominin found in the Denisova Cave in the Altai mountains of Russia provided "direct evidence for genetic mixture between Neanderthals and Denisovans on at le…
2020
#14098
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.
Expanding on previous findings by a genome wide association study of severe COVID-19, specifically with respiratory failure which had found that a gene cluster residing on chromosome 3 had a significant association wi…
1876
#14097
Beobachtungen über die Befruchtung und Entwicklung des Kaninchens and Meerschweinchens.
Hensen's node. "Hensen’s research focused on the embryonic development of guinea pigs and rabbits. While studying those organisms he noticed something previously undiscovered—an enlarged area above the primitive strea…
1929
#14096
Gestaltungsanalyse am Amphibienkeim mit Örtlicher Vitalfärbung: II. Teil. Gastrulation und Mesodermbildung bei Urodelen und Anuren.
Modern fate mapping began in 1929 when Walter Vogt marked the groups of cells using a dyed agar chip and tracked them through gastrulation.
1905
#14095
Grundzüge einer Biologie der menschlichen Plazenta. Mit besonderer Berücksichtig der Fragen der fötalen Ernährung.
Discovery of Hofbauer cells, oval eosinophilic histiocytes with granules and vacuoles found in the placenta, which are of mesenchymal origin, in mesoderm of the chorionic villus, particularly numerous in early pregnan…
1916
#14094
The differentiation of cells as a criterion for cell identification, considered in relation to the small cortical cells of the thymus.
First use of the term "stem cells" in English. Digital facsimile from rupress.org at this link.
1868
#14093
Palaeontological memoirs and notes of the late Hugh Falconer. For many years superintendent of the H.E.I. Company's botanical gardens at Suharunpoor and Calcutta. With a biographical sketch of the author. Compiled and edited by Charles Murchison. Vol. 1. Fauna Antiqua Sivalensis. Vol. II. Mastodon, elephant, rhinoceros, ossiferous caves, primeval man and his cotemporaries. 2 vols.
Falconer's writings on human antiquity appear in Vol. 2 of his Palaeontogical memoirs. Together with William Pengelly, Falconer was one of the first two scientists to visit Brixham Cave after its discovery in 1858, an…
1901
#14092
Die Neven-verteilung in der Haut in ihrer Beziehung zu den Erkrankungen der Haut. Beilage zu den Verhandlungen der Deutschen Dermatologischen Gesellschaft VII Congress.
At the Seventh Congress of the German Dermatological Society held in 1901Blaschko presented observations of a rare dermatological condition involving patterned skin lesions S-shaped on the abdomen, V-shaped over the u…
1964
#14091
Isolation, structure, and partial synthesis of an active constituent of hashish.
Mechoulam and Gaoni showed that the active ingredient of "one of the most widely used illicit narcotic drugs," the flowering tops of Cannabis sativa, is "pure tetrhydrocannabinol" (THC). This they called the "psychoto…
2022
#14090
The contagion of liberty: The politics of smallpox in the American revolution.
"The Revolutionary War broke out during a smallpox epidemic, and in response, General George Washington ordered the inoculation of the Continental Army. But Washington did not have to convince fearful colonists to pro…
1973
#14089
Rh: The intimate history of a disease and its conquest.
1938
#14088
Icterus gravis (erythroblastosis) neonatorum.
Darrow was the first to identify the cause of hemolytic disease of the newborn (HDN). Three years prior to the discovery of antibodies against the Rh antigen, Darrow correctly hypothesized that the disease was caused …
1932
#14087
Erythroblastosis fetalis and its association with universal edema of the fetus, icterus gravis neonatorum and anemia of the newborn.
The authors described and named this syndrome/illness of newborns for the first time, including pathological findings, clinical data, lab abnormalities, presentation and course of illness. Order of authorship in the o…
2004
#14086
L’origine de la syphilis en Europe: Avant ou après 1493? / The origin of syphilis in Europe: Before or after 1493? Proceedings of an international colloquium, Toulon, France, 25–28 November 1993. Edited by Olivier Dutour, György Pálfi, Jacques Berato, and Jean-Pierre Brun.
The occasion of this meeting was the discovery in 1989 near Hyères (Var, France) of a human skeleton of the third or fourth century CE presenting lesions similar to those of syphilis. The volume contains fifty papers …
2006
#14085
A Devonian tetrapod-like fish and the evolution of the tetrapod body plan.
The authors showed that: 1) This transitional species had a set of features representing a major departure from the pattern in more primitive sarcopterygian fishes. 2) They presented data to indicate that Tiktaalik li…
2006
#14084
The pectoral fin of Tiktaalik roseae and the origin of the tetrapod limb.
In 2004 Shubin, Daeschler and Jenkins discovered the first well-preserved Tiktaalik fossils in on Ellesmere Island in Nunavut, Canada. Tiktaalik is a non-tetrapod member of Osteichthyes (bony fish) from the late Devon…
2009
#14083
Ardipithecus ramidus and the paleobiology of early hominids.
The authors provide evidence that Ardipithecus may be the beginning of the evolutionary pathway that eventually led to hominids. This pathway was distinct from the evolutionary pathway that led to extant African apes.…
2009
#14082
Icons of life: A cultural history of human embryos.
"Icons of Life tells the ... story of ... the Carnegie Institution of Washington's project to collect thousands of embryos for scientific study. Lynn M. Morgan blends social analysis, sleuthing, and humor to trace the…
2002
#14081
A biographical dictionary of women healers. Midwives, nurses, and physicians.
2004
#14080
Die Frühgeschichte der mittelalterlichen medizinischen Fachsprache im Deutschen: Bd 1: Untersuchungen. Bd 2: Wörterbuch.
2000
#14079
Historiografía de la psiquiatría española.
"This work contains the bibliographic references of 1,457 published studies (from 1859 to 1997) on the history of Spanish psychiatry in all its aspects: general and local overviews, biographies and pathobiographies, e…
1984
#14078
Bibliographie de l'homéopathie: Publications en langue française de 1824 à 1984.
1999
#14077
The faces of homoeopathy.
"The history of homeopathic medicine as seen through the people who contributed towards its development. Focusing on homeopathy in the USA and in the UK, it traces the development of the practice through the 1800s, th…
2001
#14076
The heritage of homoeopathic literature: An abbreviated bibliography and commentary.
"... an abbreviated bibliography of 915 of the best and the worst of homeopathic literature from 1810 to 2000.... the book presents the work by category (Materia Medica, Repertory, Domestic Manuals, etc.) and in chron…
1988
#14075
Les livres anciens de médecine et de pharmacie. Catalogue de la Bibliothèque municipale de Toulouse.
Catalogue of books on the subjects up to 1815 held by this library.
2007
#14074
Gustaf Retzius: A Biography by Thomas Lindblad. With special contributions by Gunnar Grant, Björn Afzelius, Olle Johansson & Markku Virtanen, Helge Rask-Andersen, Torstein Sjøvold. Editor: Ove Hagelin.
A finely written and superbly illustrated and produced study of Retzius's life and published works, issued in the style of Retzius's magnificent publications.
2000
#14073
Three dimensional structure of the Tn5 synaptic complex transposition intermediate.
The authors provided a molecular framework for understanding transposition phenomena at the molecular level, including molecular images at 2.3Å resolution of the Tn5 transposase complexed to its respective Tn5 transpo…