Latest Entries

1976

#14222

Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus.

The authors studied 5 diabetic patients and first realized that A1c was an ideal index to reveal the overall control of a patient’s blood sugar over the past several months before a doctor’s visit. They were the first…

2023

#14221

The Kirtsos historical library of homoeopathic medicine: An annotated bibliographical catalogue.

The definitive bibliographical catalogue of the historical literature of homeopathy.

2012

#14220

Medicinal plants of Central Asia: Uzbekistan and Kyrgystan.

"... the first English-language book detailing medicinal plant diversity in the region. More than two hundred of the most important medicinal plants of Central Asia are listed and it includes many whose medicinal uses…

1996

#14219

Jean Fery: A sixteen century case of dissociative identity disorder.

Abstract: "This discussion reinterprets a sixteenth-century case of possession and exorcism ashttps://archive.org/details/lapossessiondeje00bour/page/n7/mode/2up Dissociative Identity Disorder (DID), formerly known as…

2021

#14218

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.

Using the base editor enzyme developed by Liu (GM11865), the authors report that they can “correct the pathogenic HGPS mutation in cultured fibroblasts derived from children with progeria and in a mouse model of HGPS.…

2003

#14217

Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

The authors showed that mutations in lamin A (LMNA) are the cause of Hutchinson-Gilford progeria sundrom (HGPS). At the end of their abstract they stated that "The discovery of the molecular basis of this disease may …

1970

#14216

Hammond's wall atlas of human anatomy.

With pages measuring 731 x 536 mm., this is the largest anatomical atlas ever published with plastic overlays. The covers include metal grommets so that the book could be hung on the wall. The work was undated, but is…

1825

#14215

Elements of operative midwifery.

Davis introduced a number of improvements in instruments and techniques: “It outlines rules and precautions for undertaking operations, described the use of various forms of forceps, and provided twenty detailed plate…

1859

#14214

Neue Untersuchungen über den Bau des Rückenmarks. 2 vols. (Text and atlas.)

Stilling carried out some of the 19th century’s most detailed and precise examinations of the spinal cord, which “laid the foundation for the modern anatomical study of the spinal cord, medulla oblongata, and pons” (C…

1843

#14213

Ueber die Textur und Function der Medulla oblongata. 2 vols. (Text and atlas).

“In this book, there are many transverse section figures from the origin of the 2nd cervical nerve pair up to the pons. Stilling aimed to reveal the difference between the spinal cord and medulla oblongata by presenti…

1983

#14212

Evidence for plasmid mediated toxin production in Bacillus anthracis.

The authors illustrated and proved that “heating V770-NPI-R containing anthrax strains, to exactly 42.5 degrees centigrade, as Pasteur and colleagues reported in GM 14211, essentially ‘cured’ these strains of their pl…

1883

#14211

De l'Atténuation des virus, avec la collaboration de MM. Chamberland, Roux et Thuillier. Quatrième Congrès international d'hygiène et de démographie. Séance du 5 Septembre 1882.

In his seminal 1880 paper, Sur les maladies virulentes, et en particulier sur la maladie appelée vulgairement choléra des poules, GM-2537, Pasteur developed the idea of a protective inoculation by attenuated living cu…

1784

#14210

Die Deutsche [sic] Giftpflanzen, zur Verhütung der tragischen Vorfälle in den Haushaltungen, nach ihren botanischen Kennzeichen, nebst den Heilungsmitteln.

On poisonous plants in Germany, for prevention of tragic household accidents, and remedies for the poisons. Illustrated with 16 plates. Digital facsimile from Google Books at this link.

1931

#14209

U. S. Plant patent 1. Climbing or trailing rose. Filed Aug. 6, 1930. Issued Aug. 18, 1931.

This was the first patent granted for a life form. In response to complaints from the nursery industry that the future of the plant breeding industry was jeopardized by the “pirating” of new plant varieties, President…

1991

#14208

Chicxulub Crater: A possible Cretaceous/Tertiary boundary impact crater on the Yucatán Peninsula, Mexico.

Eleven years after publication of No. 14207, Alan Hildebrand, working with Luis and Walter Alvarez, proposed that the Chicxulub Crater, discovered by Antonio-Camargo-Zanoguera and Glen T. Penfield during the 1970s, wa…

1980

#14207

Extraterrestrial cause for the Cretaceous-Tertiary extinction.

Following up on No. 14206, the authors stated that the same excess iridium areas were found in two different areas of W. Europe and in New Zealand, and posited that “the anomalous iridium concentrations at the C [reta…

1979

#14206

Experimental evidence in support of an extra-terrestrial trigger for the Cretaceous-Tertiary extinctions. (Abstract).

Iridium is a very rare element in the Earth's crust, but is found in anomalously high concentrations (around 1000 times greater than normal) in a thin worldwide layer of clay marking the boundary between the Cretaceou…

2004

#14205

Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst.

The authors in Korea, led by Woo-suk Hwang, reported the cloning of a human blastocyst using somatic cell nuclear transfer, and deriving pluripotent embryonic stem cells from that cloned blastocyst. In doing so they c…

1860

#14204

A medico-legal treatise on malpractice and medical evidence, comprising the elements of medical jurisprudence.

The first treatise on malpractice published in the United States and the first book to provide observations on the physician as an expert witness in malpractice cases. Digital facsimile from wellcomecollection.org at …

1934

#14203

The anemias.

1966

#14202

Mendelian inheritance in man; catalogs of autosomal dominant, autosomal recessive, and X-linked phenotypes.

Last expanded printed edition: 12th edition, 3 vols., 1998. "Dr Victor A. McKusick wrote an article in 1962 for the Quarterly Review of Biology titled ‘On the X Chromosome of Man’ (1). At that time, X-linkage had been…

2017

#14201

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination.

Prior to their development of the mRNA vaccine for Covid-19, Karikó and Weissman (Nobel Prize 2023) and colleagues used a novel mRNA vaccine, with base modifications created in their laboratory, to generate a protecti…

2023

#14200

Ultra-fast deep-learned CNS tumour classification during surgery.

Published "open access" 11 October 2023. https://www.nature.com/articles/s41586-023-06615-2 "Abstract: "Central nervous system tumours represent one of the most lethal cancer types, particularly among children1. Prima…

1827

#14199

Méthode nouvelle pour le traitement des déviations de la colonne vertébrale; précédée d'un examen critique des divers moyens employés par les orthopédistes modernes.

Digital facsimile from Google Books at this link.

1967

#14198

Enzyme defect associated with a sex-linked human neurological disorder and excessive purine synthesis.

Jay Seegmiller and his colleagues at NIH discovered that the rare genetic disease, Lesch–Nyhan syndrome, was due to a profound deficiency of an enzyme known as hypoxanthine guanine phosphoribosyltransferase, or HGPRT.…

1964

#14197

A familial disorder of uric acid metabolism and central nervous system dysfunction.

Lesch-Nyhan syndrome, a rare inherited disorder that affects about 1 in 380,000 live births. In their summary the authors described this as a new "syndrome consisting of hyperuricemia, mental retardation, choreoatheto…

1854 –1856

#14196

Oeuvres anatomiques, physiologiques et médicales de Galien. Traduites sur les textes imprimés et manuscrits accompagnées de sommaires, de notes, de planches et d'une table des matières. Précédées d'une introduction ou étude biographique, littéraire et scientifique sur Galien par Charles Daremberg. 2 Volumes.

Digital facsimile from the Hathi Trust at this link.

1924

#14195

The scrotum as a temperature regulator for the testes.

Moore and Quick established that the scrotal sac, and its ability to expand or contract, helps to regulate the temperature of the testes. Through this mechanism it enables sperm production and supports the viability o…

1878

#14194

La théorie des germes et ses applications à la médecine et à la chirurgie. Lecture faite à l'Académie de médecine par M. Pasteur en son nom et au nom de MM. Joubert et Chamberland ....

In this speech Pasteur first introduced the term "germ theory" and defined its applications in medicine, surgery, and infectious disease. The speech was first published in condensed form in Comptes rendus...de l'Acadé…

1971

#14193

The American Association of Orthodontists: The biography of a specialty organization.

1929

#14192

The action of ephedrine, pseudoephedrine and epinephrine on the bronchioles.

Swanson showed that just 0.01 mg. of epinephrine was as vasconstrictive as 2 mg. of ephedrine and 4 mg. of pseudoephedrine. He also showed that all three of these drugs have bronchodilator properties, but epinephrine …

1959

#14191

A history of the American Dental Association 1859-1959.

1958

#14190

History of dental laboratories and their contributions to dentistry.

1982

#14189

Corps infirmes et sociétés : Essais d'anthropologie historique.

Translated into English by William Sayers as A history of disability. New foreward by David T. Mitchel and Sharon L. Snyder. Ann Arbor: The University of Michigan Press, 2019. "The first book to attempt to provide a f…

1861

#14188

Stammering and stuttering, their nature and treatment.

1857

#14187

A treatise on the cure of stammering, with a general account of the various systems for the cure of impediments in speech and a notice of the life of the late Thomas Hunt.

1980

#14186

Speech disorder in nineteenth century Britain. The history of stuttering.

2020

#14185

Single particle cryo-EM at atomic resolution.

The authors located individual atoms with a protein molecule for the first time using cryo-EM. This was the highest resolution imaging of a single protein molecule achieved to date using cryo-EM. Order of authorship o…

1984

#14184

Cryo-electron microscopy of viruses.

Dubochet and colleagues introduced "Dubochet's vitrification method" to vitrify water by cooling it so rapidly that it solidified to form a glass instead of crystals. Using this method, the authors published the first…

1981

#14183

Computer averaging of electron micrographs of the 405 ribosomal subunit.

Frank and colleagues developed a method that allows sorting of particle images into classes based on their orientation, as well as their structural features. Specifically Frank developed mathematical tools used for im…

1975

#14182

Three-dimensional model of purple membrane obtained by electron microscopy.

The invention of Cryogenic electron microscopy (cryo-EM). The novel technique was achieved by "by applying the method to tilted specimens, and using the principles put forward by De Rosier and Klug (GM - 13935), for t…

1858

#14181

Compendium der Biochemie. 2 vols.

Kletzinsky coined the term "Biochemie" (biochemistry). Digital facsimile from the Hathi Trust at this link.

1832

#14180

Traité theorique et pratique de la ligature des artères.

Manec was head of anatomy at the Facultè de Médecine de Paris and a surgeon at the Salpetrière. He wrote text of his atlas on ligations of arteries in the first person based upon his experience performing the operatio…

1812

#14179

Anatomie du gladiateur combattant, applicable aux beaux arts . . . .

Salvage's 21 plates after his own drawings "are based on three casts of bodies dissected to different anatomical layers and set in the pose of the Borghese Gladiator. For these casts he preferred to use the bodies of …

1813

#14178

Recherches historiques sur la médecine des chinois.

The first Western history of Chinese medicine. Lepage, a pupil of Pierre Sue, was a friend and colleague of pioneer sinologist Jean-Pierre Abel-Rémusat. In his medical thesis Lepage presented an overview of what was t…

1825

#14177

Commentatio de vera materiae sanguini purpureum colorem impertientis natura.

Engelhart’s dissertation, presented before the medical faculty at the University of Göttingen, contains the first determination of the molecular mass of a protein (hemoglobin). Engelhart proved that the ratio of iron …

1815

#14176

Sketches of the medical schools of Paris.

Crosse, a British surgeon whose name appears without the final "ed" on the title page, was a British surgeon who spent the winter of 1814-15 in Paris, where he wrote numerous letters to friends in london and Dublin de…

1985

#14175

Identification of a novel force-generating protein, kinesin involved in microtubule based motility.

The authors discovered and named a second motor protein, and named it kinesin. Digital text from PubMedCentral at this link. Order of authorship in the original publication: Vale, Reese, Sheetz. (Thanks to Juan Weiss …

1965

#14174

Dynein: A protein with adenosine triphosphate activity from cilia.

IN 1963 Gibbons discovered a novel protein on microtubules. In 1965 he purified two regions of the protein, known as its two "arms" and named the protein dynein. This protein converts the chemical energy stored in ATP…

1936

#14173

Dermographisme et mastocytose.

Sézary and colleagues first reported systemic mastocytosis.