Facets

1953

#256.4

Helical structure of crystalline deoxypentose nucleic acid.

In 1962 Wilkins shared the Nobel Prize in Physiology or Medicine with Crick and Watson "for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living…

1953

#7993

The Welch Medical Library indexing project.

A progress report on this pioneering information retrieval project. Digital facsimile from PubMedCentral at this link.

1953

#13946

Evidence for 2-chain helix in crystalline structure of sodium deoxyribonucleate.

Franklin and Gosling's completed Patterson synthesis of the A-form of DNA, based on work begun in 1952, represents the first independent confirmation that the Watson-Crick double-helix model was correct. "We suggest t…

1953

#14290

Switching systems as mechanized brains.

Written in the earliest days of automatic switching systems when few electronic computers existed, Meszar's paper raised the question of whether certain aspects of human thought are computable and others are not. Mesz…

1954

#2883.01

The use of ultrasonic reflectoscope for the continuous recording the movements of heart walls.

Echocardiography, from which the field of medical ultrasonics developed.

1954

#4256.2

Nephrotomography. A preliminary report.

With W. Dubilier and J. C. Monteith.

1955

#2700.2

Cineradiography with an image amplifier: a practical technique.

Electron optical image intensifier, 1953.

1955

#6928

The crystal structure of the hexacarboxylic acid derived from B12 and the molecular structure of the vitamin.

The final structure of vitamin B12. With J. Pickworth, J.H. Robertson, K.N. Trueblood, R.J. Prosen, J. G. White. In 1964 Hodgkin was awarded the Nobel Prize in Chemistry "for her determinations by X-ray techniques of …

1955

#7913

VESALIUS: Official Journal of the International Society for the History of Medicine. 1-

Past issues may be viewed at: http://www.vesalius.org.uk/issues/past-issues.

1955

#9037

Biographical memoirs of fellows of the Royal Society.

http://rsbm.royalsocietypublishing.org/content/by/year/royobits "November 1955 "Obituaries of Royal Society Fellows first appeared in 1830, in Proceedings of the Royal Society of London. Initially obituaries were read…

1956 –1960

#86.4

Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.

Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…

1957

#2681

Progress in the techniques of soft tissue examination by 15 MC pulsed ultrasound. In: Ultrasound in biology and medicine, ed. E. Kelly, pp. 30-48.

1957

#2883.21

Ultrasonic Doppler method for the inspection of cardiac functions.

Demonstration of the Doppler shift in the frequency of ultrasound backscattered by moving cardiac structures.

1957

#6663

MEDICAL HISTORY. 1-

The latest issue may be viewed at https://www.cambridge.org/core/journals/medical-history/latest-issue. Vols. 1-60 (1957-2016) are archived at PubMedCentral at this link.

1958

#2682

Investigation of abdominal masses by pulsed ultrasound.

Donald, J. MacVicar and T. G. Brown used an ultrasound scanner to investigate the pregnant abdomen (see also No. 6235.1).

1959

#6908

Reasoning foundations of medical diagnosis.

The beginning of the development of clinical decision support systems (CDSS) — interactive computer programs, or expert systems, designed to assist physicians and other health professionals with decision making tasks,…

1959

#12655

Programs with Common Sense. IN: Mechanisation of thought processes, Proceedings of the Symposium of the National Physics Laboratory, pages 77-84.

"Programs with Common Sense was probably the first paper on logical AI, i.e. AI in which logic is the method of representing information in computer memory and not just the subject matter of the program. The paper was…

1959

#13334

Transfusions et greffes de moelle osseuse homologue chez des humains irradiés a haute dos accidentellement.

Order of authorship in the original publication: Mathé, Jammet, Pendic et al. Mathé performed the first bone marrow graft between unrelated donors and hosts in order to save six Yugoslavian nuclear researchers who had…

1960

#10488

The atlases of ophthalmoscopy: A bibliography, 1850-1960.

1960

#12654

Recursive functions of symbolic expressions and their computation by machine, Part 1.

The original paper on LISP, the first programming language designed for symbolic computation, which made the development of artificial intelligence programming possible. Part 2 was never published. Digital text from j…

1961

#2700.3

Isolated flying spot detection of radiodensity discontinuities displaying the internal structural pattern of a complex object.

Oldendorf described his experimental system for reconstructing the appearance of soft tissues by measuring radiodensity discontinuities (differences in tissue attenuation) but it was not fully recognized that very hig…

1961

#6235.1

Demonstration of tissue interfaces within the body by ultrasonic echo sounding.

Biparietal fetal cephalometry by ultrasound.

1962

#2924.3

Cine-coronary arteriography.

Coronary arteriography. Sones first performed this technique in 1958, and first published a more detailed account of it in a 1960 book chapter: "Cinecardioangiography," pp. 130-144 in B. L. Gordon (ed.) Clinical cardi…

1962

#256.12

Adult frogs derived from the nuclei of single somatic cells.

Demonstration that somatic and germinal nuclei are genetically equivalent. Using somatic cell nuclear transfer (SCNT), Gurdon (Nobel Prize 2012) transplanted cell nuclei from mature intestinal tadpole cells into enucl…

1962

#10506

Atlas of the British flora.

A pioneering large-scale project in plant distribution cartography, containing 10-km square distribution maps for all non-critical native and frequently occurring alien vascular plant species found in Britain and Irel…

1963 –1966

#273

Geschichte der Mikroskopie. 3 vols.

A biographical history.

1963

#7947

The MEDLARS story at the National Library of Medicine.

Digital facsimile from the Internet Archive at this link.

1963

#8149

Representation of a Function by its Line Integrals, with Some Radiological Applications.

Cormack showed that changes in tissue density could be computed from x-ray data. Because of limitations in computing power no machine was constructed during the 1960s. Cormack's papers generated little interest until …

1963

#12427

Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells.

McCulloch and Till discovered the blood-forming stem cell, the hematopoietic stem cell (HSC), through their pioneering work in mice. McCulloch and Till began a series of experiments in which bone marrow cells were inj…

1963

#12428

The distribution of colony-forming cells among spleen colonies.

Evidence that stem cells are capable of self-renewal. (Order of authorship in the original publication: Siminovitch, McCullch, Till). Digital facsimile from tspace.library.utoronto.ca at this link.

1964

#3161.1

The history of electrocardiography.

Reprinted with new introduction by Joel D. Howell, San Francisco, Norman Publishing, 1990.

1964

#2702.2

Classic descriptions in diagnostic roentgenology. 2 vols.

A compilation of pioneer contributions to the technology and methodology of diagnostic roentgenology.

1964

#2924.4

Transluminal treatment of arterioschlerotic obstruction; description of a new technic and a preliminary report of its application.

Percutaneous transluminal coronary angioplasty.

1964

#8174

HPP-64-1 DENDRAL-64-A system for computer construction, enumeration and notation of organic molecules as three structures and cyclic graphs. Interim report to the National Aeronautics and Space Administration, December 15, (1964).

DENDRAL is considered the first expert system because it automated the decision-making process and problem-solving behavior of organic chemists. The project consisted of research on two main programs, Heuristic Dendra…

1965

#2702.3

The trail of the invisible light. From X-Strahlen to Radio(bio)logy.

A great deal of valuable information presented in a not always serious manner.

1965

#7356

Use of computers in biology and medicine.

1965

#8834

Computers in biomedical research. Edited by Ralph W. Stacy and Bruce Waxman. 2 vols.

Section A, Chapter 2: "New mathematical methods in the life sciences" by George B. Dantzig. Section D, Chapter 12: "The application of computers to electroencephalography" by Mary A. B. Brazier. Section E, Chapter 13:…

1965

#11463

Fetal development as determined by ultrasonic pulse echo techniques.

Order of authorship in the original publication: Thompson, Holmes, Gottesfeld, Taylor. This was the first paper on the use of ultrasound in obstetrics and gynecology published in the United States.

1965

#14035

The nature of the Negri Body.

The first visual proof, by publication of electron micrographs at 25,000 magnification, that Negri bodies contain enormous numbers of rabies virus particles. Digital facsimile from rupress.org at this link. (Thanks to…

1966

#11105

Antibiotic susceptibility testing by a standardized single disk method.

The disk diffusion test, or agar diffusion test, or Kirby–Bauer test (disc-diffusion antibiotic susceptibility test, disc-diffusion antibiotic sensitivity test, KB test), for the antibiotic sensitivity of bacteria. (T…

1966

#14064

"Fertile" intestine nuclei.

Gurdon and Uehlinger replaced the cell nucleus of frog ova with frog intestinal nuclei to generate tadpoles, some of which became fertile adult male and female frogs. In 2012 the Nobel Prize in Physiology or Medicine …

1967

#2419.4

Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis.

Treponemal hemagglutination (TPHA) test.

1967

#2924.5

Selective coronary arteriography. Part I: A percutaneous transfemoral technic.

Selective percutaneous transfemoral arteriography.

1967

#5509.4

Rubella-virus hemagglutination-inhibition test.

With five co-authors.

1967

#273.1

The evolution of the microscope.

1967

#7699

Sémiologie graphique: Les diagrammes. Les reseaux. Les cartes.

Foundational work in design and cartography concerning the graphic display of quantitative information. Includes display of medical or statistical information. Translated into English by William J. Berg as Semiology o…

1967

#7902

HISTOIRE DES SCIENCES MÉDICALES. 1-

Issues may be viewed online at http://www2.biusante.parisdescartes.fr/hsm/?do=list.

1968

#273.2

Early history of the electron microscope.

1968

#7948

Evaluation of the MEDLARS demand search service.

The first large-scale evaluation of a "major operating information system." A detailed analysis of the performance of the Medical Literature and Analysis System (MEDLARS) in relation to 300 actual "demand search" requ…

1968

#13935

Reconstruction of three-dimensional structures from electron micrographs.

Klug and deRosier invented methods for two-dimensional and three-dimensional digital image processing of electron microscope images. The latter method provided the theory behind the development of computed tomography …