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Recently added and updated annotations in the corpus.

1982

#11414

Women in nineteenth century American botany; a generally unrecognized constituency.

Digital facsimile from jstor.org at this link.

1969

#11413

Transexualism and sex reassignment. Edited by Richard Green and John Money.

Probably the first scientific book on transsexuality issued by a university press. "Transsexualism and Sex Reassignment had its origins in the advisory board meetings of the Henry Benjamin Foundation. In the earliest …

2009

#11412

Foul bodies: Cleanliness in early America.

1820 –1821

#11411

Neueste phytochemische Entdeckungen zur Begründung einer wissenschaftlichen Phytochemie. 2 vols.

On pp. 144-146 of vol. 1 Runge reported the isolation of relatively pure caffeine for the first time. He called it "Kaffebase." Digital facsimile from Google Books at this link. In 1821 the French chemists Pierre-Jose…

1806

#11410

La découverte d'un nouveau principe végétal dans le suc des asperges.

Isolation of Asparagine, the first amino acid to be isolated.

2016

#11409

Whole-genome characterization and strain comparison of VT2f-producing Escherichia coli causing hemolytic uremic syndrome.

Order of authorship in the original publication: Grande, Michelacci, Bondi.... Demonstration that a phage infecting E. coli conveys the genes into the E. coli that code for the production of the verotoxin that causes …

1997

#11408

The complete genome sequence of Escherichia coli K-12.

Order of authorship in the original publication: Blattner, Plunkett, Bloch.... Complete genome sequence of E. coli, the first complete genome sequence of an organism. Following p. 1462 there are two large, unpaginated…

1742

#11407

An mortis incertae signa minus incerta a chirurgicis quam ab aliis experimenti?

Between the mid-1700s and the early 1900s many physicians lost confidence in their ability to declare legal death. This phenomenon was in part sparked by Winslow, whose dissertation claimed the existence of a death-li…

1992

#11406

Rudolf Virchow Sämtliche Werke. Herausgegeben von Christian Andree. 71 vols. anticipated.

From the number of volumes planned we may conclude that Virchow was one of the most prolific of all physicians. According to the Wikipedia article on Christian Andree, to which I have linked, volumes in this set were …

1959

#11405

The discovery of Dicumarol and its sequels.

An historical account of the discovery of the anticoagulant Warfarin by the primary investigator. The first use for this substance was rat poison. Digital facsimile from ahajournals.org at this link.

1562

#11404

Gli ornamenti delle donne: Tratti dalle scritture d'una reina greca per m. Giovanni Marinello et diuisi in quattro libri.

A comprehensive manual by a physician on female hygiene, beauty and adornment, containing hundreds of recommendations, advice on cosmetics, and more than two dozen recipes for dyes to bleach hair blond. Marinello reco…

1809

#11403

Observationes in Ordines plantarum naturales. Dissertatio prima complectens Anandrarum ordines Epiphytas, Mucedines, Gastromycos et Fungo.

Link described Polyangium, the first bacterium to be described that is still recognized today. Link also described Penicillium for the first time.

1902

#11402

Les cavernes ornées de dessins. La grotte d’Altamira, Espagne. “Mea culpa” d’un sceptique.

Cartailhac’s famous retraction of his opposition to the concept of paleolithic cave wall art, published over 20 years after Sanz de Sautuola’s discovery of the Altamira cave paintings in northern Spain. Cartailhac, on…

1940

#11401

Découverte d'une remarkable grotte ornée, au domaine de Lascaux, Montignac (Dordogne).

Lascaux, which has been called "The Sistine Chapel of the Paleolithic", was discovered on September 12, 1940 by 18-year-old Marcel Ravidat when his dog, Robot, fell into a hole. Ravidar returned to the cave with three…

2019

#11400

Artificial intelligence in medicine: Weighing the accomplishments, hype and promise.

2009

#11399

The coming of age of artificial intelligence in medicine.

Order of authorship in the original publication: Patel, Shortliffe, Stefanelli, Szolovits, Berthold, Bellazzi, Abu-Hanna. "Abstract: This paper is based on a panel discussion held at the Artificial Intelligence in Med…

2019

#11398

Pathogen genomics in public health.

"An important transformation is under way in public health. Next-generation sequencing (also called “high-throughput sequencing”) is reshaping communicable disease surveillance, allowing for earlier detection and more…

2014

#11397

Actionable diagnosis of neuroleptospirosis by next-generation sequencing.

Order of authorship in the original publication: Wilson, Naccache, Samayoa...Chiu. This research demonstrated the value of "next-generation-sequencing" in the diagnosis of a specific meningoencephalitis, a disease whi…

2005

#11396

Molecular identification of bacteria associated with bacterial vaginosis.

Order of authorship in the original publication: Fredricks, Fiedler, Marrazzo. Using molecular methods, the authors confirmed that absence or greatly reduced number of Lactobacilli was associated with vaginosis. They …

1898 –1900

#11394

Über die Beulenpest in Bombay im Jahre 1897. Gesamtbericht von der Kaiserlichen Akademie der Wissenschaften in Wien zur Studium der Beulenpest nach Indien entsendeten Commission. 2 vols. in 3.

Müller died at the age of 32 as a result of exposure to this plague.

2010

#11393

The last plague in the Baltic Region 1709-1713.

This work "offers a thorough description and analysis of the terrible plague epidemic that ravaged the Baltic region in the years between 1709 and 1713? at the same time when the region was razed by the Great Northern…

1947

#11392

Research and writings on training, conditioning, treatment of athletic injuries, and corrective work. 2 vols.

Bohm was probably the first full-time professional physician in professional sports.

2007

#11391

Plague ports: The global urban impact of bubonic plague, 1894-1901.

"A century ago, the third bubonic plague swept the globe, taking more than 15 million lives. The book tells the story of ten cities on five continents that were ravaged by the epidemic in it's initial years: Hong Kong…

1894 –1895

#11390

Chirurgie opératoire du système nerveux. 2 vols.

Among the innovations that Chipault made in neurosurgery were the removal of the underlyling dura in meningiomas, a new laminectomy technique, development of small clamps for closing a scalp incision, the treatment of…

2019

#11389

Trepanation, trephining and craniotomy: History and stories.

1873

#11388

Letter of Johns Hopkins to the trustees of "The Johns Hopkins Hospital".

The letter published in this 12-page pamphlet was dated March 10th, 1873. It outlined financier and philanthropist Johns Hopkins' planned bequest and general plans for the Johns Hopkins Hospital. Hopkins died in Decem…

1725

#11387

Theatrum medico-juridicum, continens varias easque maxime notabiles tam ad tribunalia ecclesiastico-civilia, quam ad medicinam forensem, pertinentes materias. Ex diversis optimorum authorum ... voluminibus excerptum .... Opus jctis, physicis, practicis, studiosis, chirurgis, aliisque utile et necessarium.

Digital facsimile from Google Books at this link.

2012

#11386

Children's surgery: A worldwide history.

1864 –1867

#11385

Notices sur la chirurgie des enfants.

The first general treatise on pediatric surgery. From parts publication. Translated into English by Richard J. Dunglison as Surgical diseases of infants and children, Philadelphia: Henry C. Lea, 1873. Digital facsimil…

1865

#11384

La Commission Sanitaire des États-Unis, son origine, son organisation et ses résultats avec une notice sur les hôpitaux militaires aux États-Unis et sur la réforme sanitaire dans les armées Europénnes.

Digital facsimile from BnFGallica at this link.

1927

#11383

The herbal in antiquity and its transmission to later ages.

2018

#11382

Rhetoric, medicine, and the woman writer, 1600–1700.

"How did physicians come to dominate the medical profession? Lyn Bennett challenges the seemingly self-evident belief that scientific competence accounts for physicians' dominance. Instead, she argues that the whole e…

1597

#11381

The garden of health conteyning the sundry rare and hidden vertues and properties of all kindes of simples and plants, together with the maner how they are to be vsed and applyed in medicine for the health of mans body, against diuers diseases and infirmities most common amongst men. Gathered by the long experience and industrie of William Langham, practitioner in phisicke.

An alphabetically arranged handbook of herbal remedies. The title page was misprinted 1579, but the work was actually printed in 1597. A list of the plants discussed is available from Early English Books Online at thi…

1896

#11380

L'action bactericide des eaux de la Jumna et du Gange sur le vibrion du cholera.

Hankin described the antibacterial activity of a then-unknown source in the Ganges and Jumna Rivers in India. He noted that "It is seen that the unboiled water of the Ganges kills the cholera germ in less than 3 hours…

2004

#11379

Molecular epidemiology of infectious disease.

1989

#11378

Botulinum toxin: a treatment for facial asymmetry caused by facial nerve paralysis.

First documentation of a cosmetic use for botulinum toxin (Botox). This was one of the early documented applications of a biological medical product.

1985

#11377

The association between idiopathic hemolytic uremic syndrome and infection by Verotoxin-producing Escherichia coli.

Order of authorship in the original publication: Karmali, Petric, Lim. The authors discovered that a hemolytic uremic syndrome, associated with E. coli 0157-H7 (first described in No. 11376), and which could not be cu…

1983

#11376

Hemorrhagic colitis associated with a rare Escherichia coli serotype.

Order of authorship in the original publication: Riley, Remis, Helgerson. First description in print of a particularly virulent E.coli (0157-H7) infection, for which no antibiotics were effective; the only treatment b…

2016

#11375

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody.

The cited paper was immediately followed in the same issue of Science by: John Misasi, Morgan A. Gilman, Masaru Kanekiyo et al, "Structural and molecular basis for Ebola virus neutralization by protective human antibo…

2019

#11374

A randomized, controlled trial of Ebola virus disease therapeutics.

Order of authorship in the original publication: Mulangu, Dodd, Davey.... One synthetic drug (Remdesivir, an antiviral) and 3 biologicals were used in this trial. The 3 biologicals were: REGN-EB3, a triple monoclonal …

1966

#11373

The transsexual phenomenon.

"A scientific report on transsexualism and sex conversion in the human male and female."

1964

#11372

Dominant erbliche Akrocephalosyndaktylie.

Pfeiffer syndrome, a rare genetic disorder characterized by the premature fusion of certain bones of the skull (craniosynostosis) which affects the shape of the head and face. In addition, the syndrome includes abnorm…

1974

#11371

Proceedings of the second Interdisciplinary Symposium on Gender Dysphoria Syndrome. Edited by Donald R. Laub and Patrick Gandy.

A symposium held at the Stanford University School of Medicine, February 2-4, 1973. It is probable that this is the first separate publication on the medical and surgical aspects of transsexuality -- male to female an…

2007

#11370

Transsexual and other disorders of gender identity: A practical guide to management. Edited by James Barrett.

1974

#11369

The surgical construction of male genitalia for the female-to-male transsexual.

Order of authorship in the original publication: Noe, Birdsell, Laub.

2015

#11368

The genealogy of a gene: Patents, HIV/AIDS, and race.

"Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied “genealogy” of CCR5—intellectual property, natural selection, Big and Sma…

2019

#11367

Allied medicine in the Great War: The medical front and the people who fought.

2013

#11366

Reconstructing faces: The art and wartime surgery of Gillies, Pickerill, McIndoe and Mowlem.

1996

#11365

Identification of a major co-receptor for primary isolates of HIV-1.

Order of authorship in the original publication: Deng, Liu, Ellmeier.... This paper was immediately followed in the same issue of Nature by: Tatjana Dragic, Virginia Litwin, Graham P. Allaway et al. "HIV-1 entry into …

1859

#11364

A manual of operative surgery on the dead body.

Smith's concept was the teaching of surgery in a manner analogous to the teaching of anatomy--i.e. from a cadaver. His book organizes and explains the operations that student surgeons could practice on a cadaver. Digi…