Latest Entries
Recently added and updated annotations in the corpus.
1989
#13569
Identification of the cystic fibrosis gene: Cloning and characterization of complimentary DNA.
The authors first published a ‘map’ of the cystic fibrosis (CF) gene and on p. 1071, they published an illustration/schematic model of the predicted CFTR (cystic fibrosis transmembrane conductance regulator). They fir…
1989
#13568
Identification of the cystic fibrosis gene: Chromosome walking and jumping.
Utilizing the chromosome "walking and and jumping" technique developed by Collins, the authors showed how they cloned the cystic fibrosis locus on the basis of its chromosomal location without the benefit of genomic r…
2002
#13567
Invisible invaders: Smallpox and other diseases in Aboriginal Australia 1780-1880.
"An epidemic of smallpox among Aboriginal people around the infant colony of Sydney in 1789 puzzled the British, for there had been no cases on the ships of the First Fleet. Where, then, did the epidemic come from? "A…
2018
#13566
Luminous creatures: The history and science of light production in living organisms.
1996
#13565
Crystal structure of Aequorea victoria green fluorescent protein.
Tsien and colleagues published the crystal structure of the 238 A.A. long green fluorescent protein (GFP). With this data, the authors could determine what had to be modified within the protein in such a way that the …
1994
#13564
Green fluorescent protein as a marker for gene expression.
Chalfie and colleagues showed that the green fluorescent protein (GFP) from the jellyfish Aequorea victoria, could be used as a visible marker for protein localization and expression in vivo, in bacteria and worm cell…
1920
#13563
The nature of animal light.
Digital facsimile from Google Books at this link. Harvey later published Living light (1940) and Bioluminescence (1952). The 1952 book extended over 600 pages, and was his definitive study. (Thanks to Malcolm Jay Kott…
1962
#13562
Extraction, purification and properties of Aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea.
Shimomura reported the discovery of green fluorescent protein (GFP) in a single footnote in this paper that was otherwise devoted to an entirely different bioluminescent protein: photoprotein aequorin. This may be the…
1931
#13561
Die hormonale Sterilisierung des weiblichen Organismus.
Halberlandt, professor of physiology at Innsbruck, invented the first hormonal contraceptive, Infecundin, using corpus luteum extracts from females rich in the hormone progesterone. His initial report on the contracep…
1958
#13560
The suppressor-mutator system of control of gene action in maize.
In this paper McClintock described a novel mobile genetic element that she called Suppressor-Mutator (Spm), and its complex regulation. She discovered that Spm could switch back and forth between an “inactive” form an…
1970
#13559
Is carbon dioxide from fossil fuel changing man's environment?
Keeling developed the first instrument that could measure carbon dioxide in atmospheric samples with consistently reliable accuracy, and in 1958 began collecting carbon dioxide samples from a base he established at Ma…
1951
#13558
Space medicine: The human factor in flights beyond the earth. Edited by John P. Marbarger.
Includes chapters by Maj. Gen. Harry G. Armstrong, Wernher von Braun, Hubertus Strughold, Heinz Haber and others.
1767
#13557
A comparative history of the increase and decrease of mankind in England, and several countries abroad, according to the different soils, situations, business of life, use of the non-naturals, &c. faithfully collected from, and attested by, above three hundred vouchers, and many of them for a long course of years, in two different Periods. To which is added a syllabus of the general States of health, air, seasons, and food for the last three hundred years; and also a meteorological discourse.
Digital facsimile from Google Books at this link.
1991
#13556
Witchcraft and hysteria in Elizabethan London: Edward Jorden and the Mary Glover case.
1990
#13555
Sleepless souls: Suicide in early modern England.
"Sleepless Souls is a social and cultural history of suicide in early modern England. It traces the rise and fall of the crime of self-murder and explores why suicide came to be harshly punished in the sixteenth centu…
1981
#13554
Mystical Bedlam: Madness, anxiety, and healing in seventeenth-century England.
"Mystical Bedlam explores the social history of insanity of early seventeenth-century England by means of a detailed analysis of the records of Richard Napier, a clergyman and astrological physician, who treated over …
1603
#13553
A brief discourse of a disease called the suffocation of the mother. Written uppon occasion which hath beene of late taken thereby, to suspect possession of an evill spirit, or some such like supernaturall power. Wherin is declared that divers strange actions and passions of the body of man, which the common opinion, are imputed to the Divell, have their true naturall causes, and do accompanie this disease.
Jorden was the first English physician who viewed women accused of witchcraft as unfortunate persons suffering from some medical condition. "Asserting that there were natural causes for their afflictions, Jorden often…
#13552
A catalogue of rare syphilis books held in the Special Collections Department of the University of Glasgow.
https://www.gla.ac.uk/media/Media_389083_smxx.pdf Describes and illustrates in color over 200 rare books from the 15th century to 1820, including those in the Hunterian Collection, with links to more extensive online …
1968
#13551
Evolutionary rate at the molecular level.
Using complex mathematics, Motoo Kimura calculated that genomes constantly undergo a remarkably high number of mutations per unit of time. He wrote, "Calculating the rate of evolution in terms of nucleotide substituti…
1996
#13550
Manuscripts and drawings in the ornithology and Rothschild libraries of The Natural History Museum at Tring. British Ornithologists' Club Occasional Publications No. 2.
The Natural History Museum at Tring, located in the grounds of the former Rothschild family home of Tring Park, was originally the private museum of Lionel Walter, 2nd Baron Rothschild. The building was constructed in…
1776
#13549
Medicinisch-praktischer Unterricht für die Feld- und Landwundärzte der österreichischen Staaten. 2 vols. [& Supplement:] Die in dem medicinisch-praktischen Unterrichte für die Feld-und Landwundärzte vorkommende Arzneymittel.
This work on "Practical medical lessons for field and land surgeons of the Austrian states," includes a 91-page appendix containing 319 recommended pharmaceuticals for the treatments described in the text. The formula…
1669
#13548
Il tabacco opera ... Nella quale si tratta dell'origine, historia, coltura, preparatione, qualità natura, virtà & uso in fumo, in polvere, in foglia, in lambitivo, et in medicina della pianta volgarmente detta tabacco, si discorre degl'vtili ch'arreca moderatamente preso, de i danni ch'apporta smoderatamente usato, e qual sia il vero e legitimo modo di prenderlo: trattato naturale, medico, morale & curioso.
Discusses the origin, history, cultivation, preparation, nature and virtues of tobacco, whether used for smoking, snuffing, chewing, etc. or for medicinal purposes (Waring). "The custom of smoking, its role in divinat…
1572
#13547
Instruction sur l'herbe petum ditte en France l'herbe de la Royne ou Medicée: Et sur la racine MECHIOCAN principalement (avec quelques autres simples rares et exquis) exemplaire à manier philosophiquement tous autres vegetaux.
The earliest treatise in French on tobacco, including its usage in medicine, and probably the earliest separate treatise on tobacco in any language. Digital facsimile from the Internet Archive at this link. See Bowen,…
1588
#13546
De medico hebraeo: Enarratio apologica ... Apposita sunt praeterea, non paucorum amplissimorum principum, quam multa decreta, in hebraeorum fauorem constituta. Annectuntur, quinetiam, in tractatus calce, nonnulla aurea dicta; ex priscorum hebraeorum monumentis excerpta; nunc primum, latinitate donata, & ad studiosorum vtilitatem, in lucem edita. Dauid de Pomis, medico physico hebraeo, auctore.
De Pomis was a rabbi and physician. "... on account of the edict of Pius IV forbidding Jewish physicians to attend Christians (1555), he moved from town to town in Italy before he settled in 1569 in Venice, where he p…
1758
#13545
Petri Loefling... Iter Hispanicum, eller Resa til spanska länderna uti Europa och America förrättad infrän år 1751 til år, 1756, med Beskrifningar och ron öfver de märkvärdigaste växyer, utgifven efter dess frånfälle af Carl Linnaeus.
Edited by Carl Linnaeus after the early death of Pehr Löfling, who Linnaeus considered his most gifted disciple. This is the account of Löfling's mostly botanically oriented researches through Spain, Portugal, and nor…
c. 1475
#13544
Secreta mulierum et virorum (cum commento).
This work on the physiology and procreative "secrets" of women was attributed to Albertus Magnus, but is now thought to have been written by one of his disciples. It was one of the most widely printed medical works in…
1845
#13543
Recherches historiques, zoologiques, anatomiques et paléontologiques sur la girafe, (Camelopardalis giraffa, Gmelin).
First comprehensive (124pp., 17 plates) anatomical study of the giraffe, conducted during a 20 day dissection of the huge animal in Toulouse. The authors entrusted the dissection to the Toulouse taxidermist, H. Traver…
1769
#13542
Consideraciones politico-medicas sobre la salud de los navegantes, en que se exponen las causas de sus mas frecuentes enfermedades, modo de precaverlas, y curarlas. Con las conducentes instrucciones para el mejor régimen de los cirujanos de navíos, que hacen viage à la América, especialmente para los de la Real Compañia Guipuzcoana de Caracas, à fin de que con mayor acierto se conduzcan, asi en el méthodo curativo de los enfermos, como en el manejo de los botiquines de su cargo.
A treatise specifically concerning the health of sailors of the Real Compañia Guipuzcoana de Caracas (Royal Guipuzcoan Company of Caracas)-- Basque traders who had a monopoly on the Venezuelan trade. Digital facsimile…
1997
#13541
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA.
Rice and colleagues constructed a viral RNA genome with the 3’ region and a consensus region to exclude potential inactivating mutations, which was then injected into the liver of chimps. That RNA, specifically encode…
1978
#13540
Transmissible agent in non-A, non-B hepatitis.
The first paper recording the discovery of what was, eleven years later in 1989, named the hepatitis C virus (see No. 12653). Harvey Alter and colleagues inoculated the serum/plasma of 4 patients with non-A/non-B hepa…
1827
#13539
Pathological and practical observations on spinal diseases: illustrated with cases and engravings. Also, An inquiry into the origin and cure of distorted limbs.
Harrison founded the first infirmary for spinal diseases in London. See Weiner & Silver, "Edward Harrison and the treatment of spinal deformities in the nineteenth century," J. R. Coll. Phys. Edinb., 38 (2006) 265-71.…
1719
#13538
Caput Bonae Spei hodiernum, das ist: vollständige Beschreibung des africanischen Vorgebürges der Guten Hofnung. Worinnen in dreyen Theilen abgehandelt wird, wie es heut zu Tage, nach seiner Situation und Eigenschaft aussiehet; ingleichen was ein Natgur-Forscher in den dreyen Reichen der Natur....
Includes the first study of the natural history of the Cape region of South Africa. Translated into English by "Mr. Medley" as The present state of the Cape of Good-Hope. 2 vols., London, 1738-31. Digital facsimile of…
2020
#13537
Abortion in America and the law in America: Roe v. Wade to the present.
2004
#13536
The history of medicine in Iran. Entries extracted from the Encyclopaedia Iranica Vols. I-XII.
1993
#13535
Medicinal plants and enigmatic health practices of Northern Ethiopia.
1959
#13534
The health seekers of Southern California 1870-1900.
1992
#13533
Hippocrate.
![HIPPOCRATES, [Ἱπποκράτης; Hippocrates of Kos] (-460 – -370)](/media/portraits/50)
Translated into English by M. B. DeBevoise as Hippocrates, Baltimore: The Johns Hopkins University Press, 1999.
2013
#13532
The PKU paradox: A short history of a genetic disease.
2015
#13531
Expelling the plague: The Health Office and the implementation of quarantine in Dubrovnik, 1377-1533.
2014
#13530
The black doctors of colonial Lima: Science, race, and writing in colonial and early Republican Peru.
"In this groundbreaking study on the intersection of race, science, and politics in colonial Latin America, José Jouve Martín explores the reasons why the city of Lima, in the decades that preceded the wars of indepen…
2017
#13529
Nahrungsmittel in der arabischen Medizin. Das Kitāb al-Aġḏiya wa-l-ašriba des Naǧīb ad-Dīn as-Samarqandī. Edition, Übersetzung und Kontext von Juliane Müller.
2014
#13528
Muslim midwives: The craft of birthing in the premodern Middle East.
1952
#13527
Hypnodontics: Hypnosis in dentistry.
"Accepted by the American Dental Association."
1959
#13526
Quantitative studies of tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of Runt Disease.
First description of what became known as Graft-versus-host disease (GvDH). This the authors initially called "graft against host (GAH)." The authors cited three conditions, later known as the Billingham criteria, whi…
1950
#13525
Lysogenicity in Escherichia coli strain K-12.
Discovery of phage λ (lambda phage). According to estherlederberg.com, only about 100 people received the first issue of Microbial Genetics Bulletin, a typed and mimeographed publication. Digital facsimile from esther…
2021
#13524
REGN-COV-2, a neutralizing antibody cocktail, in outpatients with Covid-19.
The authors showed that the Regeneron antibody cocktail has a low incidence of side effects and a profound and rapid effect on viral load, with most reduction occurring within 48 hours, even in patents with the highes…
2020
#13523
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters.
The authors, working at Regeneron, showed that a cocktail of two potent neutralizing monoclonal antibodes reduced virus load in the airways and diminshed viral induced pathological sequelae when given both as a prophy…
1912
#13522
The influence of caffeine on mental and motor efficiency. Columbia Contributions to Philosophy and Psychology, Vol. XX, No. 4.
"The Coca-Cola Company, facing a lawsuit from the federal government under the Pure Food and Drug Act, approached Hollingworth (after James McKeen Cattell and several other psychologists turned them down)[4] about inv…
1841
#13521
The pathology of drunkeness, or the effects of alcoholic drinks with drawings of the drunkard's stomach.
Including four chromolithographed plates by J. H. Hall, Albany, N.Y., this is the earliest illustrated book published in the U.S. on the pathological effects of alcoholism. Digital facsimile from the U.S. National Lib…
2020
#13520
Covid-19 and Kawasaki disease: Novel virus and novel case.
Published online 4-7-20; in print in June, 2020. First case report of what became known as Multisystem Inflammatory Syndrome in Children (MIS-C), sometimes present with Kawasaki disease. This is one of the worst compl…