Facets

1823

#1492.1

Commentatio de examine physiologico organi visus et systematis cutanei.

Purkynĕ was first to examine the interior of the human eye and the dog eye, using only a candle and a concave spherical lens. He thus invented the ophthalmoscope three decades before Helmholtz (1851; No. 5866). Reprin…

1830

#2611

A short tract on the formation of tumours, and the peculiarities that are met with in the structure of those that have become cancerous; with their mode of treatment.

Contains the first illustrations of microscopic sections of cancer; however, Home drew no worthwhile conclusion from his microscopic studies. Digital facsimile from the Internet Archive at this link.

1837

#539

Symbolae ad anatomiam villorum intestinalium, imprimis eorum epithelii et vasorum lacteorum.

Henle first described the epithelia of the skin and intestines, and defined the structure and function of columnar and ciliated epithelium. He applied the term “epithelium” to all mucous membranes in the body. Modern …

1844 –1845

#267.1

Cours de microscopie. 1 vol. and atlas.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotog…

1865

#6873

Photographs (coloured from life) of the diseases of the skin.

The first dermatologic publication illustrated with photographs.

1868

#6872

Clinique photographique de l'hôpital Saint-Louis.

The first French dermatologic book illustrated with photographs. Originally issued in fascicules, 1867-68. The first edition includes 49 or 50 albumin photographs; second edition, entitled Clinique photographique des …

1871 –1872

#10585

Photographic review of medicine and surgery. A bi-monthly illustration of interesting cases, accompanied by notes. Edited by F.F. Maury [and] L.A. Duhring. Vols. 1 & 2 (All published).

The leading 19th century American publication of artistic medical photography. Each of the two volumes includes 24 mounted photographs. The photographs ilustrate cases of unusual and extreme disease, such as gross def…

1872

#13212

Autumnal catarrh (Hay fever) with three maps.

Wyman conducted experiments that convinced him that ragweed was a cause of hay fever. He then collected data from correspondents and published the first pollen maps of the U.S. so that sufferers could plan vacations i…

1875

#10451

The geographical distribution of heart disease and dropsy, cancer in females & phthisis in females, in England and Wales. Illustrated by six small and three large coloured maps.

Haviland used the national mortality statistics for England and Wales to develop an elaborate geographical explanation based on map analysis for the cause of heart, cancer, and tuberculosis deaths. He found that femal…

1880

#3996

Photographic illustrations of skin diseases.

Fox, who was Professor of Dermatology in New York, produced a valuable atlas of skin diseases.

1880

#6874

Tratado clinico iconografico de dermatologia quirurgica.

The first medical text in Spanish to use photographs as illustrations. Includes 17 lithographed plates (12 chromolithographs) and 3 original photographs (2 hand-colored). Giné y Partagás was a surgeon, dermatologist, …

1886 –1890

#7744

Klinicheskii sbornik po dermatologii i sifilologii. 4 vols.

Mansurov was the first dermatologist in Russia, and one of the first physicians to use photography systematically in medical illustration. This was a periodical, illustrated with original photographs, of which Manusro…

1890

#2332

Weitere Mittheilungen über ein Heilmittel gegen Tuberkulose.

In 1890, Koch announced the discovery of tuberculin, a substance derived from tubercle bacilli, which he thought was capable of arresting bacterial development in-vitro and in animals. This news gave rise to tremendou…

1891 –1893

#534.68

Human monstrosities. 4 vols.

The first large work on the subject illustrated primarily by photographs of specimens, and one of the last to use to the term "monster" as a medical descriptor. Digital facsimile of the 4 volumes from the Internet Arc…

1891

#10598

A practical treatise on diseases of the skin

The first systematic treatise on dermatology published in America. Piffard was a pioneer of "indoor" magnesium flashlight photography, and took most of the 50 photographs reproduced in this book by this technique. Dig…

1892

#2545.1

Practical results of bacteriological researches.

Sternberg demonstrated that the serum of an animal recovered from vaccinia possesses the property of neutralizing the activity of the causative virus. His test was readily adaptable for use in various host-systems.

1896

#2550

Recherches de la réaction agglutinante dans le sang et le sérum desséchés des typhiques et dans la sérosité des vesicatoires.

Developing the work of Gruber and Durham, Widal noted that a patient’s serum could be tested with bacteria of known type and his disease identified by this means. They demonstrated specific agglutinins in the blood of…

1896

#2001

Sur les radiations émises par phosphorescence.

The discovery of radioactivity – research stimulated by Roentgen’s discovery of x rays. In 1903 Becquerel received half of the Nobel Prize in Physics 1903 "in recognition of the extraordinary services he has rendered …

1897

#2002

Demonstration eines mit Röntgenstrahlen behandelten Falles von Naevus pigmentosus pilosus.

First use of x rays for deep irradiation therapy.

1897

#2550.1

Über specifische Reactionen im keimfreien Filtraten aus Cholera, Typhus und Pestbouillonculturen, erzeugt durch homologes Serum.

The precipitin reaction, employed for the qualitative identification of antigens and antibodies. English translation in Bibel, Milestones in immunology,(1988) pp. 265-68.

1897

#10597

Skin diseases of children. With twelve photogravure and chromographic plates, and sixty illustrations in the text.

Digital facsimile from the Internet Archive at this link.

1898

#2003

Sur une substance nouvelle radio-active, contenue dans la pechblende.

The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…

1901

#2553

Sur l’existence de substances sensibilisatrices dans la plupart des sérums antimicrobiens.

The Bordet–Gengou complement-fixation reaction is the basis of many tests for infection, notably the Wassermann test for syphilis, and reactions for gonococcus infection, glanders, hydatid disease. English translation…

1901

#4003

Note sur le traitement du lupus érythémateux par des applications de radium.

First application of radium in the treatment of lupus.

1902

#2625

Die Lehre von den Geschwülsten. 2 vols.

“With this book the microscopical epoch in the evolution of the knowledge of cancer may be said to have been brought to a close” (Haagensen).

1902

#2625.1

Cancroid des rechten Handrückens.

Frieben reported the carcinogenic effect of x-rays in man.

1904

#2561

Blood immunity and blood relationship, a demonstration of certain blood relationships amongst animals by means of the precipitin test for blood.

1904

#4004

Surla radiothérapie des teignes.

Sabouraud’s method of radiological treatment of ringworm.

1905 –1906

#5440

The histology of the skin lesions in varicella.

Tyzzer was first to recognize inclusion bodies in varicella.

1908

#5065

Kutanreaktion beil Impfung mit Diphtherietoxin.

The Schick test for the determination of susceptibility to diphtheria.

1911

#2637.1

Le cancer expérimental.

Experimental production of malignant tumors by means of x rays.

1913

#5066

Die Diphtherietoxin – Hautreaktion des Menschen als Vorprobe der prophylaktischen Diphtherieheilseruminjektion.

Schick developed his test for use as an indication as to whether or not prophylactic injections of antitoxin are necessary in children already exposed to diphtheria. English translation in J. Mt. Sinai Hosp., 1938, 5,…

1913

#13264

Beiträge zur Pathologie und Klinik der Mammacarcinome.

In a study of 3,000 mastectomies, Salomon compared X-rays of the beasts (mammograms) to the actual removed tissue, paying close attention to microcalcifications. In doing so he was able to establish the difference in …

1915

#2569

The influence of the x-ray on the production of antibodies.

Proof that x rays suppress the antibody response.

1919

#2440

On the value of a skin reaction to a suspension of leprous nodules.

Mitsuda (lepromin) reaction. English translation by the author in Int. J. Leprosy, 1953, 21, 347-58.

1919 –1920

#3850

Epinephrin hypersensitiveness test in the diagnosis of hyperthyroidism.

Goetsch devised a skin reaction test for use in the diagnosis of hyperthyroidism

1919

#3922

A system of blood analysis.

Folin–Wu test for blood sugar.

1924

#5069

Ueber cutane Hautreaktion mittels Diphtherie-Toxin zum Nachweis der Diphtherie-Immunität.

The “scratch test”, a cutaneous reaction for determination of susceptibility to diphtheria.

1926

#2650

Haemagglutinegehalte van het bloedserum bij carcinoompatiënten.

Bendien test for the diagnosis of cancer. He published books in German and English on this subject in 1931. Modification by E. C. Lowe, Brit. med. J., 1932, 2, 1060.

1927

#2008

Discordance des effets des rayons X, d’une part dans la peau, d’autre part dans le testicule, par le fractionnement de la dose: diminution de l’efficacité dans la peau, maintien de l’efficacité dans le testicule.

Dose fractionation.

1931

#3923

The analysis of whole-blood. II. The determination of sugar and of saccharoids (non-fermentable copper-reducing substances).

Benedict’s test for blood-sugar.

1937

#12832

Electrophoresis of serum globulin. II- Electrophoretic analysis of normal and immune sera.

Tiselius showed that an antibody that he produced in a rabbit by immunizing it with albumin (ovalbumin) was clearly located in the gamma globulin fraction. He summarized the paper with this statement: "Investigation o…

1939

#3098

Studies on leukemia with the aid of radioactive phosphorus.

Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…

1940

#2010.2

Acceleration of electrons by magnetic induction.

Betatron. Continued as Kerst, "The acceleration of elecrons by magnetic induction," Phys. Rev., 60 (1941) 47-52. Digital facsimile of the 1941 paper at this link.

1940

#3099

Nuclear physics and therapy: preliminary report on a new method for the treatment of leukemia and polycythemia.

Radio-phosphorus in treatment of leukemia.

1946

#2659.5

The design of a proton linear accelerator.

Linear ion accelerator. In 1968 Alvarez received the Nobel Prize in Physics "for his decisive contributions to elementary particle physics, in particular the discovery of a large number of resonance states, made possi…

1946

#9338

Radioactive iodine therapy: Effect on functioning metastases of adenocarcinoma of the thyroid.

Seidlin and Marinelli described the first successful treatment of a patient with thyroid cancer metastases using radioiodine (I-131). This paper demonstrated the potential of nuclear medicine as a medical specialty.

1950

#2352

A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.

1950

#2660.2

A sensitive directional gamma-ray detector.

Directional scintillation detector probe. Cassen assembled the first automated scanning system, comprised of a motor driven scintillation detector coupled to a relay printer. The scanner was initially used to image th…

1956 –1960

#86.4

Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.

Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…