Facets

1582

#7327

Aigentlich Beschreibung der Raiss, so er vor diser Zeit gegen Auffgang inn die Morgenländer, fürnemlich Syriam, Iudaeam, Arabiam, Mesopotamiam, Babyloniam, Assyriam, Armeniam etc....

Rauwolf provided the first modern descriptions of the flora of the area east of the Levantine coast. He was also the first to describe the riparian flora of the Euphrates, and the first European to publish an account …

1628

#2011

Methodus facile parandi iucunda tuta et nova medicamenta & eius applicatio aduersus chimicos.

Page 170 includes the first definite description of a blood transfusion, notably published in the same year as Harvey's discovery of the circulation of the blood in De motu cordis. Digital facsimile from Google Books …

1665 –1666

#2012

The method observed in transfusing the blood out of one live animal into another.

In February 1665 Lower successfully transfused dogs with blood.

1665

#1962

Clysmatica nova; oder newe Clystier-Kunst.

Elsholtz’s book on the venous infusion of medicaments was one of the first works to deal with blood transfusion. Latin edition in 1667; English translation in 1677. Reprint of Latin 1667 edition, Hildesheim, G. Olms, …

1667

#2013

Lettre … touchant deux expériences de la transfusion faites sur des hommes.

The first transfusion of blood into a human was performed by Denis on June 15, 1667; he transfused lamb’s blood into a youth. For a partial translation, see Geoffrey Keynes’s Blood transfusion (Bristol, 1949) 14-15. D…

1667

#2014

An account of the experiment of transfusion, practised upon a man in London.

First transfusion of blood performed on a human in England, Nov. 23, 1667.

1679

#10604

Tractatio med. curiosa, de ortu & occasasu transfusionis sanguins, qua haec, quae fit e bruto in brutum, a for medico penitus eliminatur; ila, quae e bruto in hominem peragitur....

The first detailed history of efforts at blood transfusion. Mercklin was one of the earliest writers to discuss the history, value, dangers, and methods of blood transfusion. He recognized and understood what we now c…

1780

#8589

Experiments establishing a criterion between mucaginous and purulent matter. An an account of the retrograde motions of the absorbent vessels of animal bodies in some diseases.

Includes the first description of the value of digitalis in the treatment of patients with heart failure, with discussion of several successful cases. Digital facsimile from Google Books at this link. Darwin and Withe…

1785

#1836

An account of the foxglove, and some of its medical uses.

Before publication of Withering's book digitalis was a widely used folk remedy, occasionally mentioned in the literature. Withering established the correct dosages, and the action of digitalis in edema and on the hear…

1799

#11592

An essay on the medical properties of the digitalis purpurea or foxglove.

"John Ferriar...published the first monograph on digitalis after William Withering (1785). Ferriar was the first to suggest that digitalis was beneficial in dropsy (severe congestive heart failure), in part because it…

1802 –1803

#2028.4

Die Transfusion des Blutes und Einspriitzung der Arzneyen in die Adem. Historisch und in Rücksicht auf die practische Heilkunde bearbeitet. 2 vols.

Schell was the author of the first 2 vols, which were the first major work on transfusion since the 17th century and an excellent early history of the subject. Scheel reviewed both transfusion and intravenous injectio…

1817

#9701

On transfusion of blood in extreme cases of haemorrhage.

In 1816 Leacock, from Barbados, reported systematic experiments in Edinburgh on dogs and cats that established that donor and recipient must be of the same species, and recommended inter-human transfusion; he then ret…

1817

#9871

De nova infusionis methodo. Dissertatio inauguralis medico-chirurgica....

Eduard von Graefe’s medical thesis described the method devised by his brother, Carl Ferdinand von Graefe (1787-1840), for transfusing blood or other liquids into the blood vessels. The work includes an illustration o…

1818

#2015

Experiments on the transfusion of blood by the syringe.

Blundell invented a syringe by means of which he was able to transfuse dogs.

1819

#2015.1

Some account of a case of obstinate vomiting, in which an attempt was made to prolong life, by the injection of blood into the veins.

Records the first human to human transfusion. A man received 12 to 14 oz. of blood from several donors by means of Blundell’s funnel and syringe. He died 56 hours after the transfusion.

1821

#2016

Examen du sang et de son action dans les divers phénomènes de la vie.

First successful use of defibrinated blood for animal transfusions. This was the first attempt to prevent coagulation during transfusion.

1828 –1829

#2017

Observations on transfusion of blood.

The first human to human transfusion in which the patient did not die. Blundell established the most fundamental points in transfusion, including the incompatibility of interspecies transfusion and the method of indir…

1836

#11556

Nouvelles recherches sur le rhumatisme articulaire en général, et spécialement sur la loi de coincidence de la péricardite et de l'endocardite avec cette maladie, ainsi que sur l'efficacité de la formule des émissions sanguines coup sur coup dans son traitement.

"In this volume he [Bouillaud] irrevocably established the etiologic relationship between rheumatic fever and heart disease. Early reports on this relationship had been contributed by Pitcairn, Jenner, and Wells, but …

1840 –1841

#3058.1

Successful transfusion of blood.

Blood transfusion used in treatment of hemophilia.

1843

#3060

Essai d’hématologie pathologique.

The first monograph on hematology in its "modern" sense. Andral established analysis of the blood on the basis of exact knowledge of the blood components. He analysed the blood fibrin and albumin. He recognized severa…

1844

#1859

Mémoire sur l’alcool amylique.

Discovery of amyl nitrite.

1845

#1860

Mémoire sur la digitale pourprée.

Isolation of an active principle in digitalis, amorphous digitalin, more potent than the plant itself.

1862

#2388

Della trasmissione delle sifilide mediante la inoculazione del sangue.

Proof of the possibility of transmission of syphilis by blood transfusion.

1867

#2890

On the use of nitrite of amyl in angina pectoris.

Lauder Brunton was responsible for the introduction of amyl nitrite for the alleviation of angina. Reprinted in F. A. Willius & T. E. Keys: Cardiac classics, 1941, pp. 561-64.

1867

#9869

Prize essay. Ancient transfusion and infusion compared with modern transfusion, infusion, and hypodermic or subcutaneous injections. Translated by Charles F. Wittig.

A comprehensive review, for the time, of the historical literature on these subjects. Digital facsimile from Google Books at this link.

1869

#2017.1

Cases of transfusion, with some remarks on a new method of performing the operation.

Sodium phosphate used as anticoagulant in blood transfusion.

1873

#2017.2

Immediate transfusion in England: seven cases, and the author’s method of operating.

Portable transfusion apparatus.

1874

#2018

Auflösung der rothen Blutzellen.

Landois discovered the hemolyzing effect of blood serum of one species when transfused into another.

1875

#1869.1

Untersuchungen über die pharmakologisch wirksamen Bestandtheile der Digitalis purpurea

Schmiedeberg isolated digitoxin from digitalis.

1876

#7215

Études historiques, physiologiques et cliniques sur la transfusion du sang.

An excellent and well-documented treatise on blood transfusion, including a comprehensive history of the subject from its beginnings in the seventeenth century to its revival in the nineteenth after a long period of d…

1879

#2892

Nitro-glycerine as a remedy for angina pectoris.

Murrell introduced trinitrin (nitroglycerin, glyceryl trinitrate) in the treatment of angina.

1883

#1875

Grundriss der Arzneimittellehre.

Schmiedeberg, leading German pharmacologist, was professor at Dorpat and Strasburg. Among his many valuable investigations may be mentioned his study of the effect of drugs on the circulation.

1885

#1881

A text-book of pharmacology, therapeutics and materia medica.

Brunton was physician to St. Bartholomew’s Hospital and an eminent pharmacologist. He is notable for his introduction of amyl nitrite in the treatment of angina pectoris and for a vast amount of other work concerning …

1887

#2908

L’artério-sclérose subaiguë dans ses rapports avec les spasmes vasculaires et son traitement par la trinitrine (nitroglycérine).

“Huchard’s disease” – continued hypertension causing arteriosclerosis. Huchard did much to develop the knowledge concerning arteriosclerosis and summarized his work in a classic monograph published in 1909.

1895

#2893

Klinisches über Diuretin.

In 1895 Askanazy proposed diuretin as a remedy for anginal pain.

1902

#2110

Snake venom in relation to haemolysis, bacteriolysis, and toxicity.

1904

#1893.1

Ueber Digalen (Digitoxinum solubile).

Introduction of digalen.

1905

#2819

New methods of studying affections of the heart.

Mackenzie established the remarkable action of digitalis in auricular fibrillation.

1909

#5628

Hemorrhage and transfusion.

1913

#2018.1

A new and simple method of transfusion.

In order to prevent blood coagulation during transfusion, Kimpton and Brown used apparatus lined with paraffin wax. See also Boston med. surg. J., 1915, 173, 425-7.

1914

#2019

Note sur une nouvelle méthode de transfusion.

Hustin demonstrated the anticoagulant powers of sodium citrate and glucose in blood transfusion.

1914

#2020

Nuevo procedimiento para la transfusion de la sangre.

Agote was the first to transfuse citrated blood. Text in Spanish and French.

1914

#2844

Die unregelmässige Herztätigkeit und ihre klinische Bedeutung.

Wenckebach was the first to demonstrate (pp. 173-75) the value of quinine (“Wenckebach’s pills”) in the treatment of paroxysmal fibrillation. The same work contains a number of excellent descriptions of various forms …

1915

#2021

A new and greatly simplified method of blood transfusion. A preliminary report.

About the same time as Agote, Lewisohn introduced the citrate method of blood transfusion. See also his later paper in Surg. Gynec. Obstet., 1915, 21, 37-47.

1916

#1904

Digitaliswirkung am isolierten Vorhof des Frosches.

An important analysis of the action of digitalis on the isolated heart.

1917 –1918

#2021.1

Transfusion with preserved red blood cells.

Robertson stored blood and used it with good results to treat casualties on the battlefield.

1918

#2848

Ueber Vorhofflimmern beim Menschen und seine Beseitigung durch Chinidin.

Following Wenckebach’s discovery of the efficacy of quinine in the restoration of normal rhythm in auricular fibrillation. Frey showed that quinidine was the most effective of the cinchona alkaloids in this respect.

1918

#3135

A clinical study of puerperal anaemia.

Four cases of pernicious anemia of pregnancy treated by blood transfusion.

1920

#2853

Verhandlungen ärtzlicher Gesellschaften und Kongressberichte.

Saxl injected a mercurial compound (Novasurol), a powerful diuretic, for the treatment of cardiac failure.

1925

#1912

The action and uses in medicine of digitalis and its allies.