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Browse across eight MeSH (opens in new tab) facets — era, geography, science, specialty, technology, history, culture, and reference. Select one tag per group; counts update across the others. What’s new in facet browse how facets relate to subjects and MeSH.
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Specialties & Disease
- Anatomy & Pathology 7
- Cardiology & Blood 94
- Neurology & Psychiatry 27
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- Infectious Disease (General) 1
- Surgery & Anesthesia 76
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Social & Historical Studies
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Reference & Scholarly Works
454 entries match Genetics & Heredity [K01.900.300]
1995
#11343
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
First sequence of the complete genome of a free-living non-viral organism—Haemophilus influenzae—the bacterium that causes lower respiratory tract infections and meningitis in infants and young children. This genome c…
1995
#12364
The developing heart: A "history" of pediatric cardiology.
A memoir, largely from personal experience, of the developments in embryology, pathology, clinical features, treatment of congenital heart disease.
1997
#11408
The complete genome sequence of Escherichia coli K-12.
Order of authorship in the original publication: Blattner, Plunkett, Bloch.... Complete genome sequence of E. coli, the first complete genome sequence of an organism. Following p. 1462 there are two large, unpaginated…
1997
#14131
Proteome research: New frontiers in functional genomics.
Order of editorship in the original publication: Wilkins, Williams, Appel, Hochstrasser. "Recent advances in two-dimensional gel electrophoresis, protein microanalytsis and bioinformatics have made the large-scale, sy…
1998
#6888
Genome sequence of the nematode C. elegans: A platform for investigating biology.
Completion of the first genome of a multi-cellular organism—C. elegans. "C. elegans is a free-living nematode which is widely used as a model organism. The C. elegans genome has been fully sequenced and is therefore a…
1998
#11342
Complete genome sequence of treponema pallidum, the syphilis spirochete.
Order of authorship in the original publication: Fraser, Norris, Weinstock....Smith, Venter. Sequence of the genome of the bacterium that causes syphilis. (Thanks to Juan Weiss for this reference and its interpretation.)
1998
#11998
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Abstract: "Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tubercu…
1999
#10053
The black stork: Eugenics and the death of "defective" babies in American medicine and motion pictures since 1915.
2000
#13943
Gene therapy of severe combined immunodeficiency (SCID)-XI disease.
In 1999, With Marina Cavazzana-Calvo and Salima Hacein-Bey, Fischer achieved the first clinical successes in the world of gene therapies for about ten bubble children,[8] two of whom unfortunately developed leukaemias…
2001
#6891
Initial sequencing and analysis of the human genome.
Initial draft sequence of the human genome from the publically financed project, involving the coordinated efforts of 20 laboratories and hundreds of people around the world. The full text is available from Nature at …
2001
#6892
The sequence of the human genome.
Initial draft sequence of the human genome by Venter and the staff at Celera Genomics. The full text is available from Science at this link.
2001
#10335
Dying in the City of the Blues: Sickle cell anemia and the politics of race and health.
"Set in Memphis, home of one of the nation's first sickle cell clinics, Dying in the City of the Blues reveals how the recognition, treatment, social understanding, and symbolism of the disease evolved in the twentiet…
2002
#11336
Genome sequence of the human malaria parasite Plasmodium falciparum.
Order of authorship in the original paper: Gardner, Hall, Fung.... Genome of the Plasmodium falciparum parasite carried by the mosquito that causes malaria in humans. (Thanks to Juan Weiss for this reference and its i…
2002
#11337
The genome sequence of the malaria mosquito Anopheles gambiae.
Order of authorship in the original publication: Holt, Subramanian, Halpern.... Sequence of the genome of Anopheles gambiae, the mosquito that carries the malaria parasite, Plasmodium falciparum. (Thanks to Juan Weiss…
2003
#10863
The genome sequence of the SARS-associated coronavirus.
Dated May 30, 2003 and published immediately after No. 10862 in the same issue of Science, this reported the work of Marco Marra and his team in Canada. Order of authorship in the published paper was Marra, Jones, Ast…
2003
#14217
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
The authors showed that mutations in lamin A (LMNA) are the cause of Hutchinson-Gilford progeria sundrom (HGPS). At the end of their abstract they stated that "The discovery of the molecular basis of this disease may …
2005
#11335
Characterization of the reconstructed 1918 Spanish Influenza Pandemic virus.
Order of authorship in the original publication: Tumpey, Basler, Aguilar... Taubenberger. Reconstruction of the genome of the 1918 Spanish Influenza virus from frozen tissue samples from a mass grave of victims of the…
2005
#11339
The genome of the African trypanosome Trypanosoma brucei.
Genome of the parasite that causes Sleeping Sickness. (Thanks to Juan Weiss for this reference and its interpretation.)
2005
#11594
The eugenics movement: An encyclopedia.
2006
#9722
The genetics revolution: History, fears and future of a life-altering science.
2007
#7434
A life decoded. My genome: My life.
2007
#7954
The emergence of genetic rationality: Space, time & information in American biological science, 1870-1920.
2007
#11338
Genome sequence of Aedes aegypti, a major arbovirus vector.
Order of authorship in the original publication: Nene, Wortman, Lawson.... Sequence of the genome of the mosquito that transmits Zika, Yellow fever, Dengue, Chikungunya, etc. (Thanks to Juan Weiss for this reference a…
2007
#12965
The diploid genome sequence of an individual human.
The first genome sequence of a single human (Craig Venter), including analysis and comments on his genetic markers, and their possible medical and prognosticating implications. (Order of authorship in the original pub…
2008
#13058
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Ley and collaborators decoded all the genes of a person with cancer (acute myeloid leukemia (AML)) and found a set of mutations that might have caused the disease or aided its progression.
2010
#7290
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia.
Svante Pääbo and collaborators reconstructed the genome of the Denisova hominins and announced that they were a new species, that they interbred with our species, and that the DNA results suggest that they had dark ha…
2010
#7844
The Oxford handbook of the history of eugenics. Edited by Alison Bashford and Philippa Levine.
2011
#10972
The bleeding disease: Hemophilia and the unintended consequences of medical progress.
2011
#13571
Correction of the 508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
Negulescu and colleagues published a "proof of concept" experiment showing that the novel molecule called VX-809 could correct in vitro the very common and critical 508del-CFTR mutation identified by Collins. (See GM …
2013
#13532
The PKU paradox: A short history of a genetic disease.
2013
#14101
The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.
Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…
2014
#7289
The complete genome sequence of a Neanderthal from the Altai Mountains.
First complete sequence of a Neanderthal genome. With more than 20 co-authors. In 2022 Pääbo was awarded the Nobel Prize in Physiology or Medicine "for his discoveries concerning the genomes of extinct hominins and hu…
2014
#11340
Genome sequence of the Tsetse Fly (Glossina morsitans): Vector of African Tyrpanosomiasis.
The Internation Glossina Genome Initiative consisted of 179 collaborators. (Thanks to Juan Weiss for this reference and its interpretation.)
2014
#11341
Presence of extensive Wolbachia symbiont insertions discovered in the genome of its host Glossina morsitans morsitans.
Order of authorship in the original publication: Brelsfoard, Tsiamis, Falchetto....The authors suggested that infection by Wolbachia may give a reproductive advantage to the fly that carries the parasite causing Sleep…
2014
#11397
Actionable diagnosis of neuroleptospirosis by next-generation sequencing.
Order of authorship in the original publication: Wilson, Naccache, Samayoa...Chiu. This research demonstrated the value of "next-generation-sequencing" in the diagnosis of a specific meningoencephalitis, a disease whi…
2015
#9195
Radium and the secret of life.
2015
#14067
Evolution of Darwin’s finches and their beaks revealed by genome sequencing.
The authors sequenced the genome of 120 individuals representing all of Darwin’s finches. They found that a 240 kilobase haplotype encompassing the ALX1 gene, which encodes a transcription factor affecting craniofacia…
2016
#8539
History within: The science, culture, and politics of bones, organisms, and molecules.
2016
#9617
The gene: An intimate history.
2016
#11409
Whole-genome characterization and strain comparison of VT2f-producing Escherichia coli causing hemolytic uremic syndrome.
Order of authorship in the original publication: Grande, Michelacci, Bondi.... Demonstration that a phage infecting E. coli conveys the genes into the E. coli that code for the production of the verotoxin that causes …
2017
#10945
Genomic epidemiology reveals multiple introductions of Zika virus into the United States.
Order of authorship in the original publication: Grubaugh, Ladner, Kraemer. The authors found that the Zika virus was introduced into Florida at least 4 times, but perhaps as many as 40 times, before it was detected, …
2018
#10145
Who we are and how we got here: Ancient DNA and the new science of the human past.
2018
#14099
The genome of the offspring of a Neanderthal mother and a Denisovan father.
Paleogenomic study of a single bone fragment from a female hominin found in the Denisova Cave in the Altai mountains of Russia provided "direct evidence for genetic mixture between Neanderthals and Denisovans on at le…
2019
#11398
Pathogen genomics in public health.
"An important transformation is under way in public health. Next-generation sequencing (also called “high-throughput sequencing”) is reshaping communicable disease surveillance, allowing for earlier detection and more…
2019
#11462
A new genomic blueprint of the human gut microbiota.
Order of authorship in the original publication: Almeida, Mitchell, Boland.... Abstract: "The composition of the human gut microbiota is linked to health and disease, but knowledge of individual microbial species is n…
2020
#11877
Clades of huge phages from across Earth's ecosystems.
Order of authorship in the original publication: Al-Shayeb, Sachdeva, Chen.... Doudna. Open access, available from nature.com at this link. This paper was a collaboration of about 50 scientists of diverse regions and …
2020
#13485
Novel 2019 coronavirus genome.
https://virological.org/t/novel-2019-coronavirus-genome/319 "Novel 2019 coronavirus genome "10th January 2020 "This posting is communicated by Edward C. Holmes, University of Sydney on behalf of the consortium led by …
2020
#13776
The human gene editing debate.
"Provides a history of the debate about gene editing, a summary of the ethics, and a proposal for moving forward. Re-conceptualizes the historical discussion about gene editing in the context of today's widespread use…
2020
#14098
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.
Expanding on previous findings by a genome wide association study of severe COVID-19, specifically with respiratory failure which had found that a gene cluster residing on chromosome 3 had a significant association wi…
2021
#13478
CRISPR-Cas9 gene editing for sickle cell disease and ß-thalassemia.
First application of CRISPR gene editing in the successful cure of diseases. Order of authorship in the original publication: Frangoul, Altshuler, Cappellini. (Thanks to Juan Weiss for this reference and its interpret…