Facets

1849

#11948

Ship fever. An inaugural thesis, submitted for the degree of M.D., at Geneva Medical College, Jan. 1849.

Elizabeth Blackwell was the first woman to graduate M.D. in the United States. This paper on typhus was her first publication, and is thus the first publication in America by a woman physician educated in the United S…

1902

#3780

On the pathological changes in Hodgkin’s disease, with especial reference to its relation to tuberculosis.

Dorothy Reed’s classic work on Hodgkin’s disease included a study of the histological picture. She described the proliferation of the endothelial and reticular cells, and the formation of lymphadenoma cells – “Dorothy…

1921

#5287

Studies on the treatment of human trypanosomiasis with tryparsamide (the sodium salt of N-phenylglycineamide-p-arsonic acid).

Introduction of tryparsamide in the treatment of trypanosomiasis.

1924

#5082

A skin test for susceptibility to scarlet fever.

The “Dick test” for the determination of individual susceptibility to scarlet fever.

1924

#5082.1

The etiology of scarlet fever.

Proof that streptococcus is the cause of scarlet fever.

1924

#5083

A scarlet fever antitoxin.

Following their successful attempts to establish individual susceptibility to scarlet fever, these workers prepared an antitoxin for immunization.

1924

#5084

The significance of Streptococcus hemolyticus in scarlet fever and the preparation of a specific anti-scarlatinal serum by immunization of the horse to Streptococcus hemolyticus-scarlatinae.

Dochez and Sherman immunized a horse by repeated injections of scarlet fever toxin. A serum obtained from the horse blanched a scarlet fever rash and, when injected subcutaneously, caused marked amelioration of the ea…

1926

#12386

Isolation of a crystalline protein with tuberculin activity.

Siebert identified the active agent in tuberculin as a protein.

1928

#5434.1

Cultivation of vaccinia virus without tissue culture.

Introduction of “Maitland’s medium”.

1931

#4670.5

Immunological differences between strains of poliomyelitis virus.

1934

#12387

The isolation and properties of the purified protein derivative of tuberculin

Purification of tuberculin (PPD). By the 1940s Seibert's PPD was the international standard for tuberculin tests.

1937

#2348

A new tuberculin patch test.

1938

#4660

Recovery of the virus of equine encephalomyelitis from the brain of a child.

Western equine encephalitis virus recovered from man.

1938

#1952

Treatment of pneumonia with 2-(p-aminobenzenesulphonamido) pyridine.

Clinical proof of the value of sulphapyridine. M & B 693 (sulphapyridine) treatment of pneumonia. This followed the experimental work of L. E. H. Whitby (see No. 1951).

1938

#3149

Tropical macrocytic anaemia: Its relation to pernicious anaemia.

1939

#5087.2

A study in active immunization against pertussis.

Pertussis vaccine.

1940

#5224

Complement-fixation test in lymphogranuloma venereum.

Diagnosis of lymphogranuloma venereum by complement-fixation test. With G. W. Rake and M. F. Shaffer.

1940

#5259

Klinische und parasitologische Befunde und chemotherapeutische Ergebnisse bei der Hühnermalaria.

Discovery of the developmental forms of P. gallinaceum in the incubation period.

1941

#2417

A new serologically active phospholipid from beef heart.

Cardiolipin antigen for serological diagnosis of syphilis. For isolation and purification see J. biol. Chem., 1942, 143, 247-56.

1944 –1948

#2447

Indice bibliográfico de lepra, 1560-1943. 3 vols.

Supplements 1-5, 1952-62.

1947

#1940

Chloromycetin, an antibiotic with chemotherapeutic activity in experimental rickettsial and viral infections.

Introduction of chloramphenicol, used in treatment of typhus.

1955

#5546.3

Propagation and primary isolation of mumps virus in tissue culture.

1956

#2353.1

Freeze-dried B.C.G. vaccination of newborn infants with a British vaccine.

Freeze-dried B.C.G. vaccine.

1962

#10920

Powassan virus: Field investigations in Northern Ontario, 1959-1961.

The authors isolated a virus from the brain of a child who died of encephalitis in Powassan, Ontario, and named it the Powassan virus. They posited a tick vector and possible rodent natural hosts. (Thanks to Juan Weis…

1964

#2419.3

An improved FTA test for syphilis; the absorption procedure (FTA-ABS).

Absorbed fluorescent treponemal antibody (FTA-ABS) test. With W. E. Deacon and P. E. Meyer. The text is available from the NLM PubMedCentral at this link.

1967

#2419.4

Haemagglutination test utilizing pathogenic Treponema pallidum for the sero-diagnosis of syphilis.

Treponemal hemagglutination (TPHA) test.

1970

#5546.5

Lassa fever, a new virus disease of man from West Africa. III. Isolation and characterization of the virus.

Preliminary note in Nature (Lond.), 1970, 227, 174. Lassa Hemorrhagic Fever is endemic to the West African countries of Nigeria, Guinea, Liberia and Sierra Leone.

1972

#5289.4

A bibliography on Chagas’s disease (1909-1969)

Index-Catalogue of Medical and Veterinary Zoology, Special Publication No. 2.

1983

#6996

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).

Isolation of the human immunodeficiency virus (HIV-1). In 2008 Barré-Sinoussi and Montagnier shared half of the Nobel Prize in Physiology and Medicine "for their discovery of human immunodeficiency virus." The other h…

1984

#11059

A new type of retrovirus isolated from patients presenting with lymphadenopathy and acquired immune deficiency syndrome: Structural and antigenic relatedness with equine infectious anemia virus.

Order of authorship in the original publication: Montagnier, Dauguet,... Barré-Sinoussi. In this paper Montagnier and colleagues showed that, contrary to the views of Gallo and his group, LAV (Lymphadenopathy Associat…

1985

#11377

The association between idiopathic hemolytic uremic syndrome and infection by Verotoxin-producing Escherichia coli.

Order of authorship in the original publication: Karmali, Petric, Lim. The authors discovered that a hemolytic uremic syndrome, associated with E. coli 0157-H7 (first described in No. 11376), and which could not be cu…

1986

#10788

Isolation of a new human retrovirus from West African patients with AIDS.

HIV-2 was discovered essentially simultaneously by French and U.S. teams. This was the first publication by the French team. Order of authorship of the original publication was Clavel, Guettard, Brun-Vezinet. See thei…

1994

#8453

The black death.

A collection of documents written by those who lived and died in the mid-fourteenth century, translated and accompanied with commentaries.

1996

#11852

Bubonic plague in nineteenth-century China.

The first work in English on the history of disease in China traces an epidemic of bubonic plague that began in Yunnan province in the late eighteenth century, spread throughout much of southern China in the nineteent…

1998

#10900

Ehrlichia chaffeensis in Missouri ticks.

Order of authorship in the original paper: Roland, Everett, Cyr. Using PCR, the authors demonstrated that the tick Amblyoma americanum (the Lone Star Tick) was the insect vector of Ehrlichia chaffeensis. Digital facsi…

1998

#11342

Complete genome sequence of treponema pallidum, the syphilis spirochete.

Order of authorship in the original publication: Fraser, Norris, Weinstock....Smith, Venter. Sequence of the genome of the bacterium that causes syphilis. (Thanks to Juan Weiss for this reference and its interpretation.)

1999

#11040

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes.

Order of authorship in the original paper: Gao, Bailes, Robertson, Hahn. Demonstration, led by Hahn, that HIV-1 originated specifically in the chimpanzee--a mutant of the chimp SIV (SIV-cpz) which acquired mutations s…

2001

#10799

Malaria: Poverty, race, and public health in the United States.

2002

#11336

Genome sequence of the human malaria parasite Plasmodium falciparum.

Order of authorship in the original paper: Gardner, Hall, Fung.... Genome of the Plasmodium falciparum parasite carried by the mosquito that causes malaria in humans. (Thanks to Juan Weiss for this reference and its i…

2004

#10508

Mapping the Victorian social body.

"The cholera epidemics that plagued London in the nineteenth century were a turning point in the science of epidemiology and public health, and the use of maps to pinpoint the source of the disease initiated an explos…

2004

#11244

The life and death of smallpox.

2005

#10415

Fever of war: The influenza epidemic in the U.S. Army during World War I.

2005

#11193

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: A double blind randomized placebo-controlled trial.

Order of authorship in the original paper: Taylor, Makunde, McGarry.... The authors treated infection by the parasitic worm Wuchereria bancrofti, cause of elephantiasis (lymphatic filariasis), by killing the Wolbachia…

2005

#11335

Characterization of the reconstructed 1918 Spanish Influenza Pandemic virus.

Order of authorship in the original publication: Tumpey, Basler, Aguilar... Taubenberger. Reconstruction of the genome of the 1918 Spanish Influenza virus from frozen tissue samples from a mass grave of victims of the…

2005

#11339

The genome of the African trypanosome Trypanosoma brucei.

Genome of the parasite that causes Sleeping Sickness. (Thanks to Juan Weiss for this reference and its interpretation.)

2005

#13622

Suppression of RNA recognition by toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA.

Karikó and Weissman discovered the nucleoside modifications that suppress the immungenicity of RNA, leading to their patents for the application of non-immunogenic, nucleoside-modified RNA (modRNA). This technology wa…

2006

#11041

Chimpanzee reservoirs of pandemic and nonpandemic HIV-1.

Order of authorship in the original paper: Keele, Van Heuverswyn, Li, Hahn. Definitive proof that SIVcpz circulated and existed in wild chimps in a given area of Africa, and that a mutation of this specific SIV in Afr…

2007

#11338

Genome sequence of Aedes aegypti, a major arbovirus vector.

Order of authorship in the original publication: Nene, Wortman, Lawson.... Sequence of the genome of the mosquito that transmits Zika, Yellow fever, Dengue, Chikungunya, etc. (Thanks to Juan Weiss for this reference a…

2008

#10509

Cholera and nation: Doctoring the Victorian social body.

2010

#11076

Odorant reception in the malaria mosquito Anopheles gambiae.

Order of authorship in the original publication: Carey, Wang, ... Carlson. The authors showed that besides CO2, the odorant receptors in the malaria mosquistoes Anopheles gambiae are sensitive to other "mostly sweat" …