Historical Bibliography Updated: July 14, 2026
Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: A double blind randomized placebo-controlled trial.
Lancet, 365, 2116-2121. 2005.
Order of authorship in the original paper: Taylor, Makunde, McGarry.... The authors treated infection by the parasitic worm Wuchereria bancrofti, cause of elephantiasis (lymphatic filariasis), by killing the Wolbachia bacteria inside the worm with the antibiotic doxycycline. Since the worm requires the Wolbachia (a symbiont) to live, killing the Wolbachia bacteria eliminates the worm and cures the disease.
(Thanks to Juan Weiss for this reference and its interpretation.)
Facet Tags
Subjects
BACTERIOLOGY › BACTERIA (mostly pathogenic; sometimes indexed only to genus) › Rickettsiales › WolbachiaINFECTIOUS DISEASE › VECTOR-BORNE DISEASES › Mosquito-Borne Diseases › Lymphatic Filariasis (Elephantiasis)PARASITOLOGYPARASITOLOGY › Helminths › Parasitic Worms › FilariaPHARMACOLOGY › PHARMACEUTICALS › AntibioticsWOMEN, Publications by › Years 2000 -
| Catalog Metadata | Reference Information |
|---|---|
| Entry Number | #11193 |
| Permanent Link | https://beta.historyofmedicine.com/id/13390 |
| External URL | macrofilaricidal-activity-after-doxycycline-treatment-of-wuchereria-bancrofti-a-double-blind-randomized-placebocontrolled-trial |