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23 entries match Neurology & Psychiatry [C10 / F04] · Nobel Prizes [K01.150.567]

1886

#1416

Sulla fina anatomia degli organi centrali del sistema nervoso.

Golgi’s histological studies made a clear conception of the nervous system possible for the first time. He demonstrated the existence of multipolar nerve-cells (Golgi cells) by means of his silver nitrate stain, and d…

1899 –1904

#1293.1

Textura del sistema nervioso del hombre y de los vertebrados. 2 vols. in 3.

From publication in fascicules, 1897-1904 (vol. 1 in 3 pts., vol. 2 in 4 pts.) This monumental work set out the cytological and histological foundations of modern neurology. Ramón y Cajal’s research confirmed the neur…

1906

#1432

The integrative action of the nervous system.

Sherrington insisted that the essential function of the nervous system was the co-ordination of activities of the various parts of the organism. His work on the nervous system, especially his experimental studies of r…

1906

#3401

Untersuchungen über den vom Vestibularapparat des Ohres reflektorisch ausgelösten Rhythmischen und seine Begleiterscheinungen.

Bárány’s pointing test for the localization of circumscribed cerebellar lesions. Republished in book form, Berlin, 1906. In 1914 Bárány was awarded the Nobel Prize in Physiology or Medicine "for his work on the physio…

c. 1914

#1340

The action of certain esters and ethers of choline, and their relation to muscarine.

Demonstration of the inhibitory action of acetylcholine on the heart. In 1936 Dale shared the Nobel Prize in Physiology or Medicine with Otto Loewi (No. 1343) "for their studies in the chemical mediation of nervous im…

1918 –1919

#4806

Ueber die Einwirkung der Malaria auf die progressive Paralyse.

In 1917 Wagner von Jauregg returned to the idea of the inoculation of paretics with malaria to induce pyrexia, first proposed by him in 1887 (Ueber die Einwirkung fieberhafter Erkrankungen auf Psychosen, Jb. Psychiat.…

1921 –1922

#1343

Ueber humorale Uebertragbarkeit der Herznervenwirkung.

Loewi’s important experiments firmly established the theory of chemical intermediaries in nervous reactions. In 1936 Loewi shared the Nobel Prize in Physiology or Medicine with Dale "for discoveries related to chemica…

1924

#1305

The compound nature of the action current of nerve as disclosed by the cathode ray oscillograph.

In 1944 Erlanger and Gasser shared the Nobel Prize in Physiology or Medicine "for their discoveries regarding the highly differentiated functions of single nerve fibers."

1928

#1308

The basis of sensation. The action of the sense organs.

In 1932 Adrian shared the Nobel Prize in Physiology or Medicine with Charles Scott Sherrington "for their discoveries about the function of neurons." See also Nos. 1307, 1528, and 1303.

1939

#1310.1

Action potentials recorded from inside a nerve fibre.

Hodgkin and Huxley were the first to succeed in inserting electrodes into a living giant nerve fiber and to measure directly the action potential within it. In 1963 Hodgkin and Huxley shared the Nobel Prize in Physiol…

1946

#1354.1

A specific sympathomimetic ergone in adrenergic nerve fibres (sympathin) and its relations to adrenaline and nor-adrenaline.

Noradrenaline shown to be the predominant transmitter of the effects of sympathetic nerve impulses. In 1970 Euler shared the Nobel Prize in Physiology or Medicine with Katz and Axelrod "for their discoveries concernin…

1948

#1451.1

Die funktionelle Organisation des vegetativen Nervensystems.

In 1949 Hess shared the Nobel Prize in Physiology or Medicine with Egas Moniz in 1949 “for his discovery of the functional organization of the interbrain as a coordinator of the activities of the internal organs.”

1949

#4671.1

Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues.

Enders, Weller, and Robbins grew the poliomyelitis virus in cultures of different tissues. Their method proved of great value in virus research, and removed the final obstacles to vaccine production. In 1974 Enders, W…

1952

#1354.2

Different forms of signalling employed by the nervous system.

In 1970 Katz shared the Nobel Prize in Physiology or Medicine with Ulf von Euler and J. Axelrod "for their discoveries concerning the humoral transmitters in the nerve terminals and the mechanism for their storage, re…

1959

#14242

Receptive fields of single neurones in the cat's striate cortex.

Also: Hubel & Wiesel, Receptive fields, binocular interaction and functional architecture in the cat's visual cortex, J. Physiol., 160, 1962, 106-154. In 1981 Hubel and Wiesel shared half of the Nobel Prize in Physiol…

1961

#9648

Cerebral organization and behavior: The split brain behaves in many respects like two separate brains, providing new research possibilities.

Sperry and colleagues, including Michael Gazzaniga, conducted extensive experiments on an epileptic patient who had had his corpus collosum, the "bridge" between the left and right hemispheres of the brain, split so t…

1965

#14244

The stimulation of epidermal proliferation by a specific protein (EGF).

Discovery of Epidermal Growth Factor (EGF). In 1986 Cohen shared the Nobel Prize in Physiology or Medicine with Rita Levi-Montalcini "for their discoveries of growth factors."

1971

#4729.2

Transmission of two subacute spongiform encephalopathies of man (Kuru and Creutzfeldt–Jakob disease) to New World monkeys.

Following Hadlow's suggestion (1959), Gadjusek was able to transmit Kuru and Creutzfeldt–Jakob disease to primates through cerebral inoculations. Similarity in the clinical course of the diseases and in the cellular p…

1971

#14258

The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat.

See also: O'Keefe, "Place units in the hippocampus of the freely moving rat," Experimental Neurology, 51 (1976) 78–109. O’Keefe and his student Jonathan Dostrovsky discovered place cells in the hippocampus, and that t…

1982

#10140

Novel proteinaceous infectious particles cause Scrapie.

In 1997 Prusiner was awarded the Nobel Prize in Physiology or Medicine "for his discovery of Prions - a new biological principle of infection." In his 1982 paper Prusiner proposed a completely novel explanation for th…

1996

#14252

Toward a molecular definition of long-term memory storage.

"Abstract: The storage of long-term memory is associated with a cellular program of gene expression, altered protein synthesis, and the growth of new synaptic connections. Recent studies of a variety of memory process…

1998

#14251

DARPP-32: Regulator of the efficacy of dopaminergic neurotransmission.

"Greengard's research focused on events inside the neuron caused by neurotransmitters. Specifically, Greengard and his fellow researchers studied the behavior of second messenger cascades that transform the docking of…

2005

#14259

Microstructure of a spatial map in the entorhinal cortex.

May-Britt Moser and Edvard Moser and colleagues discovered grid cells, specialized types of neurons that respond to specific locations in space. They are main components of the brain's GPS. Order of authorship in the …