LANGLEY, John Newport (1852 – 1925)
1852 – 1925
4 entries in the GMN corpus.
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1889
#1329.1
On the local paralysis of peripheral ganglia, and on the connexion of different classes of nerve fibres with them.
Langley and Dickinson studied the effect of nicotine on nerve fibers, and were able by this means to make a thorough investigation of the distribution of nerve fibers.
1894
#1290
On reflex action from sympathetic ganglia.
1905
#1893.2
On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari.
Langley introduced the concept of a receptor substance present in the biological object with which a drug has to interact in order to exert its biological effect. Digital facsimile from PubMedCentral at this link.
1921
#1332
The autonomic nervous system.
Langley divided the autonomic nervous system into (1) the orthosympathetic, and (2) the parasympathetic; he defined it as an efferent system.