De naturali parte medicinae libri septem.

The earliest work devoted exclusively to physiology and the first to call the subject by that name. It was re-issued in 1554 as part of Fernel’s Medicina (No. 2271). Femel suggested that physicians should  study the human body themselves, and not accept tradition.

See Sir Charles Sherrington’s The endeavour of Jean Femel, Cambridge, 1946.  See also the English translation of the 1567 edition: The physiologia of Jean Fernel (1567). Translated and annotated by John M. Forrester. Philadelphia: American Philosophical Society, 2003.