JACOB, François (1920 – 2013)
1920 – 2013
5 entries in the GMN corpus.
1954
#13994
Induction spontanée du développement du bactériophage lambda au cours de la recombinaison génétique, chez Escherichia coli K 12.
Wollman and Jacob discovered zygotic induction. This occurs when a bacterial cell carrying the silenced DNA of a bacteriophage transfers the viral DNA along with its own DNA in its chromosome to another bacterial cell…
1958
#6894
Sur l’expression et le rôle des allèles “inductible” et “constitutif” dans la synthèse de la β-galactosidase chez des zygotes d’ “Escherichia coli.
The “PaJaMo” experiment of PArdee, JAcob, and MOnod “broke the impasse in Crick and Brenner’s comprehension of how information in the sequence of bases in DNA came to be expressed as a sequence of the amino acids in p…
1960
#13995
L'opéron: Groupe de gènes à expression coordonnée par un opérateur.
Jacob and Monod received their share of the Nobel Prize in 1965 for their discoveries concerning the operon and viral synthesis. The first operon they described was the lac operon in E. coli. Their operon theory sugge…
1961
#256.9
Genetic regulatory mechanisms in the synthesis of proteins.
In 1965 Jacob, Monod, and André Lwoff shared the Nobel Prize in Physiology or Medicine "for their discoveries concerning genetic control of enzyme and virus synthesis."
1961
#256.10
An unstable intermediate carrying information from genes to ribosomes for protein synthesis.
Demonstration of the existence of “messenger” RNA. The following paper (pp. 581-85) by F. Gros et al. is also relevant.