CHAIN, Sir Ernst Boris (1906 – 1979)
1906 – 1979
6 entries in the GMN corpus.
Image source Nobel Foundation · nobelprize.org · Public domain
1940
#1933.3
An enzyme from bacteria able to destroy penicillin.
Penicillinase.
1940
#1934
Penicillin as a chemotherapeutic agent.
Proof of the therapeutic action in vivo of penicillin against streptococcal and other bacterial infections. Building upon Fleming’s work (No. 1933 and 10784), the consequences of which had originally been widely unapp…
1941
#1934.1
Further observations on penicillin.
First report of the chemotherapeutic action of penicillin on humans (10 cases).
1942
#14282
Purification of penicillin.
Abraham and Chain first announced the purification of penicillin, a critical step before production of the drug could begin, in a two paragraph paper published on a single page of Nature on March 21, 1942. The method,…
1943
#1934.2
Penicillamine, a characteristic degradation product of penicillin.
With W. Baker.
1949
#12613
Antibiotics: A survey of penicillin, streptomycin, and other antimicrobial substances from fungi, actinomycetes, bacteria, and plants. 2 vols.
Order of authorship of the original set: H. W. Florey, Chain, Heatley, Jennings, Sanders, Abraham, M. E. Florey.