Some account of the success of inoculation for the small-pox in England and America. Together with plain instructions, by which any person may be enabled to perform the operation.

Franklin’s statistical account of smallpox inoculation in Boston during the epidemic of 1753-54, showing the beneficial effects of the practice, was written for William Heberden, who contributed the “Plain instructions” mentioned on the title. Early in his life Franklin had actively opposed inoculation but he became one of its strongest advocates after the tragic death of his son from smallpox in 1736.