The practical history of a new epidemical eruptive miliary fever, with an angina ulcusculosa, which prevailed in Boston New England in the years 1735 and 1736.

Douglass left the first adequate clinical description of scarlet fever, which he called angina ulcusculosa, in his account of New England’s first scarlet fever epidemic. He was one of the first American physicians to hold the M.D.