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Historical Bibliography Updated: July 14, 2026

Eine periodische Function des isolirten Froschherzen.

Ber. Ver. Ges. Wiss. Leipzig, 25, 11-94. 1873.

"Using an isolated frog heart preparation with ligatures around the atria, Luigi Luciani, an Italian physiologist working in 1873 in Carl Ludwig’s famous laboratory in Leipzig, was the first to demonstrate cardiac group beating, which he named periodic rhythm. He attributed this to increased resistance to impulse propagation between the atria and the ventricle. Karel F. Wenckebach, in his 1899 landmark report of group beating in a patient in which he also used pulse tracings, credited Luciani with this discovery. Wenckebach referred to the phenomena as “Luciani periods" (Upshaw & Silverman, "Luigi Luciani and the earliest graphic demonstration of Wenckebach periodicity," Circulation, 101 (2000) 2662–2668.

Catalog MetadataReference Information
Entry Number#12261
Permanent Linkhttps://beta.historyofmedicine.com/id/14478
Author Bio LinkWikipedia ↗
External URL-eine-periodische-function-des-isolirten-froschherzen

Geographic Context

Mentioned in annotation: Leipzig