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Historical Bibliography Updated: July 14, 2026

A clinical and genetic study of 1,280 cases of mental defect.

Spec. Rep. Ser. Med. Res. Coun. (Lond), No. 229. 1938.

In this exhaustive study Penrose showed (p. 36) the significance of maternal age in the etiology of Down syndrome.

Catalog MetadataReference Information
Entry Number#4962.1
Permanent Linkhttps://beta.historyofmedicine.com/id/6325
Author Bio LinkWikipedia ↗
External URLa-clinical-and-genetic-study-of-1280-cases-of-mental-defect