Historical Bibliography Updated: July 14, 2026
Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.
J. Amer. Med. Assoc., 132 (3), 126-132. 1946.
Widely considered the first uses of chemotherapy for the treatment of malignant diseases.
Subjects
| Catalog Metadata | Reference Information |
|---|---|
| Entry Number | #10133 |
| Permanent Link | https://beta.historyofmedicine.com/id/12322 |
| Author Bio Link | Wikipedia ↗ |
| External URL | nitrogen-mustard-therapy-use-of-methylbisbetachloroethylamine-hydrochloride-and-trisbetachloroethylamine-hydrochloride-for-hodgkins-disease-lymphosarcoma-leukemia-and-certain-allied-and-miscellaneous-disordersm |